Datopotamab Deruxtecan

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	GD2OWY1DTK
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Datopotamab Deruxtecan

Official Name

English

DS-1062

Code

English

DATO-DXD

Code

English

datopotamab deruxtecan [INN]

Common Name

English

Immunoglobulin G1, anti-(human tumor-associated calcium signal transducer 2) (human-Mus musculus monoclonal MAAP-9001 γ1-chain), compd. with human-Mus musculus monoclonal MAAP-9001 κ-chain, dimer, thioether with N-[6-(3-mercapto-2,5-dioxo-1-pyrrolidiny

Common Name

English

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Code System

Code

Type

Description

NCI_THESAURUS

C151967

PRIMARY

CAS

2238831-60-0

PRIMARY

USAN

LM-52

PRIMARY

FDA UNII

GD2OWY1DTK

PRIMARY

INN

11218

PRIMARY

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From	To
1_22	1_96
1_148	1_204
1_224	3_214
1_230	2_230
1_233	2_233

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Glycosylation Type

MAMMALIAN

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					FUV56ZH0GB

DNA TOPOISOMERASE 1

TARGET -> INHIBITOR

Amount:


					BA3HQU7PO9

PARENT -> CONJUGATE

Amount:


					GM1W90Y88M

TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER 2

TARGET->CONJUGATED TOXIN

Amount:

Showing 1 to 3 of 3 entries

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					OQM5SD32BQ

ACETAMIDE, N-((1S,9S)-9-ETHYL-5-FLUORO-2,3,9,10,13,15-HEXAHYDRO-9-HYDROXY-4-METHYL-10,13-DIOXO-1H,12H-BENZO(DE)PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLIN-1-YL)-2-HYDROXY-

METABOLITE ACTIVE -> PARENT

Amount:

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Type

Details


					GD2OWY1DTK

Datopotamab Deruxtecan

ACTIVE MOIETY

Amount:

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	ESTIMATED 145000 Da (average)
Molecular Formula	CHEMICAL	ESTIMATED C6464H10008O2012N1708S44

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