Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Tue Apr 01 17:51:37 GMT 2025
by
admin
on
Tue Apr 01 17:51:37 GMT 2025
|
| Protein Type | RECEPTOR |
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
GA3FU58I96
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Common Name | English | ||
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Preferred Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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GA3FU58I96
Created by
admin on Tue Apr 01 17:51:37 GMT 2025 , Edited by admin on Tue Apr 01 17:51:37 GMT 2025
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PRIMARY |
| From | To |
|---|---|
| 1_8 | 1_108 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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AGONIST -> TARGET |
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INHIBITOR -> TARGET |
Ran into kidney toxicity issues, making this an intriguing toxicology case study.
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AGONIST -> TARGET | |||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
OLT1177 reduces the release of mature IL-1? by preventing NLRP3 inflammasome oligomerization.
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
Potently inhibited palmitate-driven
IL-1b release from human PBMCs
IC50
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INHIBITOR -> TARGET |
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ACTIVATOR -> TARGET |
QS-21 as an activator of the NLRP3 inflammasome. May also form pores in endosomal membranes to facilitate peptide release.
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT | CHEMICAL |
|