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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 16:25:06 GMT 2025
Edited
by admin
on Tue Apr 01 16:25:06 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
G770V925KP
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
KHK-4083
Preferred Name English
Rocatinlimab
USAN   INN  
Official Name English
immunoglobulin G1-kappa, anti-[Homo sapiens TNFRSF4 (tumor necrosis factor receptor (TNFR) superfamily member 4, OX40, CD134)], Homo sapiens monoclonal antibody; gamma1 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV2-5*02 (94.0%) -(IGHD) - IGHJ1
Common Name English
KHK4083
Code English
rocatinlimab [INN]
Common Name English
Immunoglobulin G1, anti-(human CD134 antigen) (human monoclonal KHK4083 ?1-chain), disulfide with human monoclonal KHK4083 ?-chain, dimer
Common Name English
ROCATINLIMAB [USAN]
Common Name English
AMG451
Code English
AMG-451
Code English
Rocatinlimab [WHO-DD]
Common Name English
Code System Code Type Description
FDA UNII
G770V925KP
Created by admin on Tue Apr 01 16:25:06 GMT 2025 , Edited by admin on Tue Apr 01 16:25:06 GMT 2025
PRIMARY
CAS
2431972-52-8
Created by admin on Tue Apr 01 16:25:06 GMT 2025 , Edited by admin on Tue Apr 01 16:25:06 GMT 2025
PRIMARY
SMS_ID
100000183794
Created by admin on Tue Apr 01 16:25:06 GMT 2025 , Edited by admin on Tue Apr 01 16:25:06 GMT 2025
PRIMARY
USAN
KL-247
Created by admin on Tue Apr 01 16:25:06 GMT 2025 , Edited by admin on Tue Apr 01 16:25:06 GMT 2025
PRIMARY
NCI_THESAURUS
C184936
Created by admin on Tue Apr 01 16:25:06 GMT 2025 , Edited by admin on Tue Apr 01 16:25:06 GMT 2025
PRIMARY
INN
11800
Created by admin on Tue Apr 01 16:25:06 GMT 2025 , Edited by admin on Tue Apr 01 16:25:06 GMT 2025
PRIMARY
From To
1_22 1_97
1_144 1_200
1_220 3_214
1_226 2_226
1_229 2_229
1_261 1_321
1_367 1_425
2_22 2_97
2_144 2_200
2_220 4_214
2_261 2_321
2_367 2_425
3_23 3_89
3_134 3_194
4_23 4_89
4_134 4_194
Glycosylation Type MAMMALIAN, AFUCOSYLATED
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 4
TARGET -> INHIBITOR
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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