Rocatinlimab

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 11:24:55 GMT 2023` Edited by `admin` on `Sat Dec 16 11:24:55 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	G770V925KP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Rocatinlimab

Official Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens TNFRSF4 (tumor necrosis factor receptor (TNFR) superfamily member 4, OX40, CD134)], Homo sapiens monoclonal antibody; gamma1 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV2-5*02 (94.0%) -(IGHD) - IGHJ1

Common Name

English

KHK4083

Code

English

KHK-4083

Code

English

rocatinlimab [INN]

Common Name

English

Immunoglobulin G1, anti-(human CD134 antigen) (human monoclonal KHK4083 γ1-chain), disulfide with human monoclonal KHK4083 κ-chain, dimer

Common Name

English

ROCATINLIMAB [USAN]

Common Name

English

AMG451

Code

English

AMG-451

Code

English

Code System Code Type Description

FDA UNII

G770V925KP

Created by admin on Sat Dec 16 11:24:55 GMT 2023 , Edited by admin on Sat Dec 16 11:24:55 GMT 2023

PRIMARY

CAS

2431972-52-8

Created by admin on Sat Dec 16 11:24:55 GMT 2023 , Edited by admin on Sat Dec 16 11:24:55 GMT 2023

PRIMARY

USAN

KL-247

Created by admin on Sat Dec 16 11:24:55 GMT 2023 , Edited by admin on Sat Dec 16 11:24:55 GMT 2023

PRIMARY

NCI_THESAURUS

C184936

Created by admin on Sat Dec 16 11:24:55 GMT 2023 , Edited by admin on Sat Dec 16 11:24:55 GMT 2023

PRIMARY

INN

11800

Created by admin on Sat Dec 16 11:24:55 GMT 2023 , Edited by admin on Sat Dec 16 11:24:55 GMT 2023

PRIMARY

From	To
1_22	1_97
1_144	1_200
1_220	3_214
1_226	2_226
1_229	2_229
1_261	1_321
1_367	1_425
2_22	2_97
2_144	2_200
2_220	4_214
2_261	2_321
2_367	2_425
3_23	3_89
3_134	3_194
4_23	4_89
4_134	4_194

Glycosylation Type

MAMMALIAN, AFUCOSYLATED

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					115VXA358P

TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 4

TARGET -> INHIBITOR

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL