LICOCHALCONE B

COC1=C(\C=C\C(=O)C2=CC=C(O)C=C2)C=CC(O)=C1O

InChIKey=DRDRYGIIYOPBBZ-XBXARRHUSA-N

InChI=1S/C16H14O5/c1-21-16-11(5-9-14(19)15(16)20)4-8-13(18)10-2-6-12(17)7-3-10/h2-9,17,19-20H,1H3/b8-4+

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

PubMed

Title	Date	PubMed
(E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(2,4-dihydroxyphenyl)prop-2-en-1-one, a novel licochalcone B derivative compound, suppresses lipopolysaccharide-stimulated inflammatory reactions in RAW264.7 cells and endotoxin shock in mice.	2014-12-05	25451593
Licochalcone B inhibits growth of bladder cancer cells by arresting cell cycle progression and inducing apoptosis.	2014-03	24384411
Transcriptional suppression of the HIV promoter by natural compounds.	2003-03	12719011
Cytotoxic activity of low molecular weight polyphenols against human oral tumor cell lines.	2000-08-23	10953322
Phenolic constituents of licorice. II. Structures of licopyranocoumarin, licoarylcoumarin and glisoflavone, and inhibitory effects of licorice phenolics on xanthine oxidase.	1989-11	2632045

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:20:18 GMT 2025` Edited by `admin` on `Mon Mar 31 21:20:18 GMT 2025`
Record UNII	G7383L14F6
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

LICOCHALCONE B [MI]

Preferred Name

English

LICOCHALCONE B

Common Name

English

(2E)-3-(3,4-DIHYDROXY-2-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-2-PROPEN-1-ONE

Systematic Name

English

2-PROPEN-1-ONE, 3-(3,4-DIHYDROXY-2-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-, (2E)-

Systematic Name

English

2-PROPEN-1-ONE, 3-(3,4-DIHYDROXY-2-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-, (E)-

Systematic Name

English

Code System Code Type Description

CAS

58749-23-8