U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C16H14O5
Molecular Weight 286.2794
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of LICOCHALCONE B

SMILES

COC1=C(O)C(O)=CC=C1\C=C\C(=O)C2=CC=C(O)C=C2

InChI

InChIKey=DRDRYGIIYOPBBZ-XBXARRHUSA-N
InChI=1S/C16H14O5/c1-21-16-11(5-9-14(19)15(16)20)4-8-13(18)10-2-6-12(17)7-3-10/h2-9,17,19-20H,1H3/b8-4+

HIDE SMILES / InChI

Molecular Formula C16H14O5
Molecular Weight 286.2794
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Phenolic constituents of licorice. II. Structures of licopyranocoumarin, licoarylcoumarin and glisoflavone, and inhibitory effects of licorice phenolics on xanthine oxidase.
1989 Nov
Transcriptional suppression of the HIV promoter by natural compounds.
2003 Mar
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 04:01:32 GMT 2023
Edited
by admin
on Sat Dec 16 04:01:32 GMT 2023
Record UNII
G7383L14F6
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LICOCHALCONE B
MI  
Common Name English
(2E)-3-(3,4-DIHYDROXY-2-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-2-PROPEN-1-ONE
Systematic Name English
2-PROPEN-1-ONE, 3-(3,4-DIHYDROXY-2-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-, (2E)-
Systematic Name English
2-PROPEN-1-ONE, 3-(3,4-DIHYDROXY-2-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-, (E)-
Systematic Name English
LICOCHALCONE B [MI]
Common Name English
Code System Code Type Description
CAS
58749-23-8
Created by admin on Sat Dec 16 04:01:32 GMT 2023 , Edited by admin on Sat Dec 16 04:01:32 GMT 2023
PRIMARY
PUBCHEM
5318999
Created by admin on Sat Dec 16 04:01:32 GMT 2023 , Edited by admin on Sat Dec 16 04:01:32 GMT 2023
PRIMARY
MERCK INDEX
m6802
Created by admin on Sat Dec 16 04:01:32 GMT 2023 , Edited by admin on Sat Dec 16 04:01:32 GMT 2023
PRIMARY Merck Index
FDA UNII
G7383L14F6
Created by admin on Sat Dec 16 04:01:32 GMT 2023 , Edited by admin on Sat Dec 16 04:01:32 GMT 2023
PRIMARY
CAS
1005324-90-2
Created by admin on Sat Dec 16 04:01:32 GMT 2023 , Edited by admin on Sat Dec 16 04:01:32 GMT 2023
NON-SPECIFIC STEREOCHEMISTRY
EPA CompTox
DTXSID601317442
Created by admin on Sat Dec 16 04:01:32 GMT 2023 , Edited by admin on Sat Dec 16 04:01:32 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> CONSTITUENT ALWAYS PRESENT
LICOCHALCONE B was tested for antimicrobial activity against methicillin sensitive Staphylococcus aureus, methicillin resistant S. aureus, Micrococcus luteus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa and found to be inactive.