MEXRENOATE POTASSIUM

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H33O6.K.2H2O
Molecular Weight	492.6441
Optical Activity	UNSPECIFIED
Defined Stereocenters	7 / 7
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O.O.[K+].[H][C@@]12CC[C@@](O)(CCC([O-])=O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])[C@@H](CC4=CC(=O)CC[C@]34C)C(=O)OC

InChI

InChIKey=QADGUEZDHAWIQG-BXKVGZNMSA-M

InChI=1S/C24H34O6.K.2H2O/c1-22-8-4-15(25)12-14(22)13-16(21(28)30-3)20-17(22)5-9-23(2)18(20)6-10-24(23,29)11-7-19(26)27;;;/h12,16-18,20,29H,4-11,13H2,1-3H3,(H,26,27);;2*1H2/q;+1;;/p-1/t16-,17+,18+,20-,22+,23+,24-;;;/m1.../s1

HIDE SMILES / InChI

Molecular Formula	C24H34O6
Molecular Weight	418.5232
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 7
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	K
Molecular Weight	39.0983
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/864608

Mexrenoate potassium is an aldosterone antagonist, which was developed as an antihypertensive agent. However, this drug has never been marketed.

Approval Year

PubMed

Title	Date	PubMed
Mexrenoate potassium: a steroidal aldosterone antagonist and antihypertensive.	1977 Jun	864608

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:26:23 GMT 2023` Edited by `admin` on `Fri Dec 15 15:26:23 GMT 2023`
Record UNII	G5R44ZQ1DN
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MEXRENOATE POTASSIUM

Official Name

English

MEXRENOATE POTASSIUM [USAN]

Common Name

English

7-Methyl 21-potassium 17-hydroxy-3-oxo-17α-pregn-4-ene-7α,21-dicarboxylate dihydrate

Common Name

English

SC-26714

Code

English

PREGN-4-ENE-7,21-DICARBOXYLIC ACID, 17-HYDROXY-3-OXO-, 7-METHYL ESTER, MONOPOTASSIUM SALT, DIHYDRATE, (7.ALPHA.,17.ALPHA.)-

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID90195757