BROPERAMOLE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H18BrN5O
Molecular Weight	364.24
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

BrC1=CC=CC(=C1)C2=NN(CCC(=O)N3CCCCC3)N=N2

InChI

InChIKey=PLZMRGRLCWCLFW-UHFFFAOYSA-N

InChI=1S/C15H18BrN5O/c16-13-6-4-5-12(11-13)15-17-19-21(18-15)10-7-14(22)20-8-2-1-3-9-20/h4-6,11H,1-3,7-10H2

HIDE SMILES / InChI

Molecular Formula	C15H18BrN5O
Molecular Weight	364.24
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6968218 | https://www.ncbi.nlm.nih.gov/pubmed/6968217

Broperamole has been studied as an anti-inflammatory agent.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
inflammatory response 47 Target ID: GO:0006954 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6968217	Inhibitor 8297

PubMed

Title	Date	PubMed
Influence of broperamole, a new antiinflammatory agent, on gastrointestinal microbleeding in the dog.	1980	6968218
Pharmacological study of broperamole, a chemical novel antiinflammatory compound.	1980	6968217

Sample Use Guides

In Vivo Use Guide

24 mg/kg of broperamole in four 7-day treatment periods (each of which was preceded by a 5-day period of no treatment)

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:26:41 GMT 2023` Edited by `admin` on `Fri Dec 15 15:26:41 GMT 2023`
Record UNII	G5MIG3753N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BROPERAMOLE

Official Name

English

1-(3-(5-(M-BROMOPHENYL)-2H-TETRAZOL-2YL)PROPIONYLPIPERDINE

Common Name

English

BROPERAMOLE [USAN]

Common Name

English

broperamole [INN]

Common Name

English

PIPERIDINE, 1-(3-(5-(3-BROMOPHENYL)-2H-TETRAZOL-2-YL)-1-OXOPROPYL)-

Systematic Name

English

TR-2378

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C257