Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 09:12:07 UTC 2023
by
admin
on
Sat Dec 16 09:12:07 UTC 2023
|
| Protein Sub Type | |
| Sequence Type | COMPLETE |
| Record UNII |
G53298VN9Y
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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DB05599
Created by
admin on Sat Dec 16 09:12:07 UTC 2023 , Edited by admin on Sat Dec 16 09:12:07 UTC 2023
|
PRIMARY | |||
|
62031-54-3
Created by
admin on Sat Dec 16 09:12:07 UTC 2023 , Edited by admin on Sat Dec 16 09:12:07 UTC 2023
|
GENERIC (FAMILY) | |||
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G53298VN9Y
Created by
admin on Sat Dec 16 09:12:07 UTC 2023 , Edited by admin on Sat Dec 16 09:12:07 UTC 2023
|
PRIMARY | |||
|
m5371
Created by
admin on Sat Dec 16 09:12:07 UTC 2023 , Edited by admin on Sat Dec 16 09:12:07 UTC 2023
|
PRIMARY | Merck Index | ||
|
1591916
Created by
admin on Sat Dec 16 09:12:07 UTC 2023 , Edited by admin on Sat Dec 16 09:12:07 UTC 2023
|
PRIMARY | RxNorm | ||
|
G53298VN9Y
Created by
admin on Sat Dec 16 09:12:07 UTC 2023 , Edited by admin on Sat Dec 16 09:12:07 UTC 2023
|
PRIMARY | |||
|
106096-92-8
Created by
admin on Sat Dec 16 09:12:07 UTC 2023 , Edited by admin on Sat Dec 16 09:12:07 UTC 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
INHIBITOR -> TARGET |
Prevents FGFR ligands, such as FGF1, FGF2, FGF4, from binding to their cognate receptors, thereby inhibiting the activation of the related FGFR tyrosine kinases. Inhibition of FGFR1 by this agent may retard tumor cell proliferation and induce tumor cell death. FP-1039 may also inhibit vascular endothelial growth factor (VEGF)-induced angiogenesis. FGFR1 is a receptor tyrosine kinase upregulated in certain tumor cells and involved in tumor cellular proliferation, differentiation, angiogenesis, and survival; most ligands that bind to FGFR1 also bind to the related receptors FGFR3 and FGFR4.
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LIGAND->TARGET |
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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| Molecular Formula | CHEMICAL |
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