Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C32H26O14 |
| Molecular Weight | 634.5404 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@H]1O[C@H](CC(O)=O)CC2=C1C(=O)C3=C(O)C(=CC(O)=C3C2=O)C4=C(O)C5=C(C(O)=C4)C(=O)C6=C([C@@H](C)O[C@H](CC(O)=O)C6)C5=O
InChI
InChIKey=VTIKDEXOEJDMJP-WYUUTHIRSA-N
InChI=1S/C32H26O14/c1-9-21-15(3-11(45-9)5-19(35)36)29(41)23-17(33)7-13(27(39)25(23)31(21)43)14-8-18(34)24-26(28(14)40)32(44)22-10(2)46-12(6-20(37)38)4-16(22)30(24)42/h7-12,33-34,39-40H,3-6H2,1-2H3,(H,35,36)(H,37,38)/t9-,10-,11+,12+/m1/s1
| Molecular Formula | C32H26O14 |
| Molecular Weight | 634.5404 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Functional studies on a ketoreductase gene from Streptomyces sp. AM-7161 to control the stereochemistry in medermycin biosynthesis. | 2005 Dec 15 |
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| Self-malonylation is an intrinsic property of a chemically synthesized type II polyketide synthase acyl carrier protein. | 2005 Nov 22 |
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| Diversity in domain architectures of Ser/Thr kinases and their homologues in prokaryotes. | 2005 Sep 19 |
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| Increased expression of ribosome recycling factor is responsible for the enhanced protein synthesis during the late growth phase in an antibiotic-overproducing Streptomyces coelicolor ribosomal rpsL mutant. | 2006 Aug |
|
| Catalytic relationships between type I and type II iterative polyketide synthases: The Aspergillus parasiticus norsolorinic acid synthase. | 2006 Dec |
|
| Proteins encoded by the conservon of Streptomyces coelicolor A3(2) comprise a membrane-associated heterocomplex that resembles eukaryotic G protein-coupled regulatory system. | 2006 Dec |
|
| Heterologous production of daptomycin in Streptomyces lividans. | 2006 Feb |
|
| A framework to analyze multiple time series data: a case study with Streptomyces coelicolor. | 2006 Feb |
|
| Priming type II polyketide synthases via a type II nonribosomal peptide synthetase mechanism. | 2006 Feb 8 |
|
| An aromatic hydroxylation reaction catalyzed by a two-component FMN-dependent Monooxygenase. The ActVA-ActVB system from Streptomyces coelicolor. | 2006 Jan 6 |
|
| The malonyl transferase activity of type II polyketide synthase acyl carrier proteins. | 2006 Jun |
|
| Fogacin, a novel cyclic octaketide produced by Streptomyces strain Tü 6319. | 2006 May |
|
| [Activation of silent antibiotic synthesis in Streptomyces lividans by disruption of a negative regulator nsdA, a gene conserved in Streptomyces]. | 2006 Sep |
|
| The global role of ppGpp synthesis in morphological differentiation and antibiotic production in Streptomyces coelicolor A3(2). | 2007 |
|
| GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism. | 2007 |
|
| Possible involvement of ActVI-ORFA in transcriptional regulation of actVI tailoring-step genes for actinorhodin biosynthesis. | 2007 Apr |
|
| New pleiotropic effects of eliminating a rare tRNA from Streptomyces coelicolor, revealed by combined proteomic and transcriptomic analysis of liquid cultures. | 2007 Aug 2 |
|
| Overexpression of Shinorhizobium meliloti hemoprotein in Streptomyces lividans to enhance secondary metabolite production. | 2007 Dec |
|
| Roles of larger conductance mechanosensitive channels (MscL) in sporulation and Act secretion in Streptomyces coelicolor. | 2007 Dec |
|
| Characterization of a novel two-component regulatory system involved in the regulation of both actinorhodin and a type I polyketide in Streptomyces coelicolor. | 2007 Dec |
|
| Dissecting the component reactions catalyzed by the actinorhodin minimal polyketide synthase. | 2007 Dec 18 |
|
| Differential stringent responses of Streptomyces coelicolor M600 to starvation of specific nutrients. | 2007 Feb |
|
| Initiation of actinorhodin export in Streptomyces coelicolor. | 2007 Feb |
|
| How do antibiotic-producing bacteria ensure their self-resistance before antibiotic biosynthesis incapacitates them? | 2007 Feb |
|
| A parallel genetic algorithm for single class pattern classification and its application for gene expression profiling in Streptomyces coelicolor. | 2007 Feb 13 |
|
| Binding study of AfsK, a Ser/Thr kinase from Streptomyces coelicolor A3(2) and S-adenosyl-L-methionine. | 2007 Jan |
|
| Comparative genomic hybridizations reveal absence of large Streptomyces coelicolor genomic islands in Streptomyces lividans. | 2007 Jul 10 |
|
| Actinorhodin biosynthesis: structural requirements for post-PKS tailoring intermediates revealed by functional analysis of ActVI-ORF1 reductase. | 2007 Jul 10 |
|
| AfsR recruits RNA polymerase to the afsS promoter: a model for transcriptional activation by SARPs. | 2007 Jun 1 |
|
| Genetic characterization of two S-adenosylmethionine-induced ABC transporters reveals their roles in modulations of secondary metabolism and sporulation in Streptomyces coelicolor M145. | 2007 Nov |
|
| Role of adenosine kinase in the control of Streptomyces differentiations: Loss of adenosine kinase suppresses sporulation and actinorhodin biosynthesis while inducing hyperproduction of undecylprodigiosin in Streptomyces lividans. | 2007 Nov 16 |
|
| NsdB, a TPR-like-domain-containing protein negatively affecting production of antibiotics in Streptomyces coelicolor A3 (2). | 2007 Oct |
|
| pH shock induces overexpression of regulatory and biosynthetic genes for actinorhodin productionin Streptomyces coelicolor A3(2). | 2007 Oct |
|
| The rare earth, scandium, causes antibiotic overproduction in Streptomyces spp. | 2007 Sep |
|
| Effects of pH shock on the secretion system in Streptomyces coelicolor A3(2). | 2008 Apr |
|
| Mechanism and regulation of the Two-component FMN-dependent monooxygenase ActVA-ActVB from Streptomyces coelicolor. | 2008 Apr 18 |
|
| Characterization of a negative regulator AveI for avermectin biosynthesis in Streptomyces avermitilis NRRL8165. | 2008 Aug |
|
| FtsY affects sporulation and antibiotic production by whiH in Streptomyces coelicolor. | 2008 Jan |
|
| Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2). | 2008 Jan 29 |
|
| Comparative genomics of Streptomyces avermitilis, Streptomyces cattleya, Streptomyces maritimus and Kitasatospora aureofaciens using a Streptomyces coelicolor microarray system. | 2008 Jan-Feb |
|
| Expression and characterization of the Streptomyces coelicolor serine/threonine protein kinase PkaD. | 2008 Mar |
|
| Conditionally positive effect of the TetR-family transcriptional regulator AtrA on streptomycin production by Streptomyces griseus. | 2008 Mar |
|
| hmgA, transcriptionally activated by HpdA, influences the biosynthesis of actinorhodin in Streptomyces coelicolor. | 2008 Mar |
|
| Crystal structures of the Streptomyces coelicolor TetR-like protein ActR alone and in complex with actinorhodin or the actinorhodin biosynthetic precursor (S)-DNPA. | 2008 Mar 7 |
|
| Uncovering genes with divergent mRNA-protein dynamics in Streptomyces coelicolor. | 2008 May 7 |
|
| Localization of the ActIII actinorhodin polyketide ketoreductase to the cell wall. | 2008 Oct |
|
| Finding new pathway-specific regulators by clustering method using threshold standard deviation based on DNA chip data of Streptomyces coelicolor. | 2008 Sep |
|
| Selection of objective function in genome scale flux balance analysis for process feed development in antibiotic production. | 2008 Sep |
|
| Effects of extracellular ATP on the physiology of Streptomyces coelicolor A3(2). | 2008 Sep |
|
| Antibiotic overproduction in Streptomyces coelicolor A3 2 mediated by phosphofructokinase deletion. | 2008 Sep 12 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:13:02 GMT 2023
by
admin
on
Sat Dec 16 09:13:02 GMT 2023
|
| Record UNII |
G4HH387T6Z
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
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| Code System | Code | Type | Description | ||
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91020
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2448
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1397-77-9
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m1401
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admin on Sat Dec 16 09:13:02 GMT 2023 , Edited by admin on Sat Dec 16 09:13:02 GMT 2023
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PRIMARY | Merck Index | ||
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G4HH387T6Z
Created by
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Actinorhodin
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5280985
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DTXSID20930557
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15428-92-9
Created by
admin on Sat Dec 16 09:13:02 GMT 2023 , Edited by admin on Sat Dec 16 09:13:02 GMT 2023
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