Efarindodekin Alfa

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 15:25:01 GMT 2025` Edited by `admin` on `Wed Apr 02 15:25:01 GMT 2025`
Protein Type	FC FUSION PROTEIN
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	G3R56JK4D5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Fc fragment of human immunoglobulin G1 (1-227) [Homo sapiens IGHG1*01, hinge (1-10), CH2 N77>A (11-120), CH3 S<sup>134</sup>>C, T<sup>146</sup>>W (121-225), CHS K<sup>227</sup>>G (226-227)] fused via peptide linker <sup>228</sup>GSGGSGGSISSGLLSGRSSGP<sup

Preferred Name

English

Efarindodekin Alfa

Official Name

English

efarindodekin alfa [INN]

Common Name

English

Immunoglobulin G1 [77-alanine, 134-cysteine,146-tryptophan,227-glycine], (human ?1-chain C region C-terminal fragment) fusion protein with peptide linker (synthetic 21-amino acid) fusion protein with interleukin 12 subunit ? [252-serine,259-aspartic acid

Common Name

English

Code System Code Type Description

FDA UNII

G3R56JK4D5

Created by admin on Wed Apr 02 15:25:01 GMT 2025 , Edited by admin on Wed Apr 02 15:25:01 GMT 2025

PRIMARY

INN

13222

Created by admin on Wed Apr 02 15:25:01 GMT 2025 , Edited by admin on Wed Apr 02 15:25:01 GMT 2025

PRIMARY

CAS

2922072-00-0

Created by admin on Wed Apr 02 15:25:01 GMT 2025 , Edited by admin on Wed Apr 02 15:25:01 GMT 2025

PRIMARY

NCI_THESAURUS

C211704

Created by admin on Wed Apr 02 15:25:01 GMT 2025 , Edited by admin on Wed Apr 02 15:25:01 GMT 2025

PRIMARY

SMS_ID

300000057005

Created by admin on Wed Apr 02 15:25:01 GMT 2025 , Edited by admin on Wed Apr 02 15:25:01 GMT 2025

PRIMARY

From	To
1_134	2_129
1_9	2_9
1_6	2_6
2_343	2_354
2_270	2_316
2_239	2_325
2_384	2_389
2_262	2_312
2_147	2_205
2_41	2_101
1_630	1_668
1_609	1_741
1_582	1_655
1_524	1_551
1_425	1_641
1_396	1_419
1_357	1_368
1_276	1_316
1_147	1_205
1_41	1_101

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_448
N	1_527
N	1_638
N	1_652
N	2_259
N	2_340
N	2_377
N	2_406
N	2_482

Related Record Type Details


					G3R56JK4D5

Efarindodekin Alfa

ACTIVE MOIETY

Comments:

interleukin-12 (IL-12) analogue

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL