NELDAZOSIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H25N5O4
Molecular Weight	375.4222
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NELDAZOSIN

Structure Search

SMILES

COC1=C(OC)C=C2C(N)=NC(=NC2=C1)N3CCN(CC3)C(=O)CC(C)O

InChI

InChIKey=IOSMPEJNAQZKJT-UHFFFAOYSA-N

InChI=1S/C18H25N5O4/c1-11(24)8-16(25)22-4-6-23(7-5-22)18-20-13-10-15(27-3)14(26-2)9-12(13)17(19)21-18/h9-11,24H,4-8H2,1-3H3,(H2,19,20,21)

HIDE SMILES / InChI

Molecular Formula	C18H25N5O4
Molecular Weight	375.4222
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200590100 | https://www.drugfuture.com/synth/syndata.aspx?ID=134313 | https://apps.who.int/iris/bitstream/handle/10665/275695/WHO-EMP-RHT-TSN-2018.1-eng.pdf?sequence=1&isAllowed=y

Neldazosin, a prazosin derivative, is an alpha adrenoreceptor antagonist. It is an antihypertensive substance.

Approval Year

Patents

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:05:19 GMT 2025` Edited by `admin` on `Mon Mar 31 18:05:19 GMT 2025`
Record UNII	G3E7RO42MB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NELDAZOSIN

Official Name

English

neldazosin [INN]

Preferred Name

English

PIPERAZINE, 1-(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL)-4-(3-HYDROXY-1-OXOBUTYL)-

Systematic Name

English

1-BUTANONE, 1-(4-(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL)-1-PIPERAZINYL)-3-HYDROXY-

Systematic Name

English

(±)-1-(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL)-4-(3-HYDROXYBUTYRYL)PIPERAZINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C270

Created by admin on Mon Mar 31 18:05:19 GMT 2025 , Edited by admin on Mon Mar 31 18:05:19 GMT 2025

Code System Code Type Description

WIKIPEDIA

Neldazosin

Created by admin on Mon Mar 31 18:05:19 GMT 2025 , Edited by admin on Mon Mar 31 18:05:19 GMT 2025

PRIMARY

PUBCHEM

65908

Created by admin on Mon Mar 31 18:05:19 GMT 2025 , Edited by admin on Mon Mar 31 18:05:19 GMT 2025

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SMS_ID

100000084129

Created by admin on Mon Mar 31 18:05:19 GMT 2025 , Edited by admin on Mon Mar 31 18:05:19 GMT 2025

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FDA UNII

G3E7RO42MB

Created by admin on Mon Mar 31 18:05:19 GMT 2025 , Edited by admin on Mon Mar 31 18:05:19 GMT 2025

PRIMARY

ChEMBL

CHEMBL2106898

Created by admin on Mon Mar 31 18:05:19 GMT 2025 , Edited by admin on Mon Mar 31 18:05:19 GMT 2025

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EVMPD

SUB09184MIG

Created by admin on Mon Mar 31 18:05:19 GMT 2025 , Edited by admin on Mon Mar 31 18:05:19 GMT 2025

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NCI_THESAURUS

C66226

Created by admin on Mon Mar 31 18:05:19 GMT 2025 , Edited by admin on Mon Mar 31 18:05:19 GMT 2025

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CAS

109713-79-3

Created by admin on Mon Mar 31 18:05:19 GMT 2025 , Edited by admin on Mon Mar 31 18:05:19 GMT 2025

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INN

6315

Created by admin on Mon Mar 31 18:05:19 GMT 2025 , Edited by admin on Mon Mar 31 18:05:19 GMT 2025

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EPA CompTox

DTXSID40869512

Created by admin on Mon Mar 31 18:05:19 GMT 2025 , Edited by admin on Mon Mar 31 18:05:19 GMT 2025

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