ASPULVINONE E

OC1=C(C(=O)O\C1=C/C2=CC=C(O)C=C2)C3=CC=C(O)C=C3

InChIKey=BNNVVTQUWNGKPH-ZROIWOOFSA-N

InChI=1S/C17H12O5/c18-12-5-1-10(2-6-12)9-14-16(20)15(17(21)22-14)11-3-7-13(19)8-4-11/h1-9,18-20H/b14-9-

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Neuraminidase 21 Target ID: CHEMBL2051 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23411074	Inhibitor 8504
Aspulvinone dimethylallyltransferase (Aspergillus terreus) 1 Target ID: Aspulvinone dimethylallyltransferase (Aspergillus terreus) Sources: https://www.ncbi.nlm.nih.gov/pubmed/678538 \| DOI: 10.1016/S0076-6879(85)10089-3	Substrate 661

PubMed

Title	Date	PubMed
Cross-Chemistry Leads to Product Diversity from Atromentin Synthetases in Aspergilli from Section Nigri.	2019-02-21	30527997
A Non-canonical Melanin Biosynthesis Pathway Protects Aspergillus terreus Conidia from Environmental Stress.	2016-05-19	27133313
Induction of secondary metabolism of Aspergillus terreus ATCC 20542 in the batch bioreactor cultures.	2016-04	26603760
Spatial regulation of a common precursor from two distinct genes generates metabolite diversity.	2015-10-01	28791090
Aspulvinones from a mangrove rhizosphere soil-derived fungus Aspergillus terreus Gwq-48 with anti-influenza A viral (H1N1) activity.	2013-03-15	23411074
Effects of high salt stress on secondary metabolite production in the marine-derived fungus Spicaria elegans.	2011	21731548
A new group of aromatic prenyltransferases in fungi, catalyzing a 2,7-dihydroxynaphthalene 3-dimethylallyl-transferase reaction.	2010-05-28	20351110
Purification and characterization of dimethylallyl pyrophosphate: aspulvinone dimethylallyltransferase from Aspergillus terreus.	1978-06-27	678538

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:56:49 GMT 2025` Edited by `admin` on `Mon Mar 31 22:56:49 GMT 2025`
Record UNII	G24NR54FG4
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

ASPULVINONE E

Common Name

English

ASPERGILLIDE B1

Preferred Name

English

(5Z)-4-HYDROXY-3-(4-HYDROXYPHENYL)-5-((4-HYDROXYPHENYL)METHYLENE)-2(5H)-FURANONE

Systematic Name

English

2(5H)-FURANONE, 4-HYDROXY-3-(4-HYDROXYPHENYL)-5-((4-HYDROXYPHENYL)METHYLENE)-, (5Z)-

Systematic Name

English

Code System Code Type Description

CAS

49637-60-7