Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H6N2 |
| Molecular Weight | 118.1359 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C1=CN2C=CC=CC2=N1
InChI
InChIKey=UTCSSFWDNNEEBH-UHFFFAOYSA-N
InChI=1S/C7H6N2/c1-2-5-9-6-4-8-7(9)3-1/h1-6H
| Molecular Formula | C7H6N2 |
| Molecular Weight | 118.1359 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Post Groebke-Blackburn multicomponent protocol: synthesis of new polyfunctional imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives as potential antimicrobial agents. | 2010-12 |
|
| Ethyl 8-(4-nitro-phen-yl)imidazo[1,2-a]pyridine-7-carboxyl-ate. | 2010-11-24 |
|
| Pharmacophore modeling and 3D-QSAR analysis of phosphoinositide 3-kinase p110alpha inhibitors. | 2010-09 |
|
| Intra-periaqueductal grey microinjections of an imidazo[1,2-b]pyridazine derivative, DM2, affects rostral ventromedial medulla cell activity and shows antinociceptive effect. | 2010-03 |
|
| Modulation of carcinogen metabolizing enzymes by new fused heterocycles pendant to 5,6,7,8-tetrahydronaphthalene derivatives. | 2010-02 |
|
| Efficient one-pot synthetic protocols for iminosugar-bearing imidazo[1,2-a]pyridines from carbohydrates. | 2010-01-26 |
|
| 3-(3-Aryloxyaryl)imidazo[1,2-a]pyridine sulfones as liver X receptor agonists. | 2010-01-15 |
|
| Palladium complexes of abnormal N-heterocyclic carbenes as precatalysts for the much preferred Cu-free and amine-free Sonogashira coupling in air in a mixed-aqueous medium. | 2009-12-21 |
|
| Novel one-pot three component reaction for the synthesis of [2-(alkylsulfanyl)imidazo[1,2-a]pyridin-3-yl](aryl)methanone. | 2009-11-13 |
|
| Structure-activity relationship study of EphB3 receptor tyrosine kinase inhibitors. | 2009-11-01 |
|
| Physicochemical properties and membrane interactions of anti-apoptotic derivatives 2-(4-fluorophenyl)-3-(pyridin-4-yl)imidazo[1,2-a]pyridine depending on the hydroxyalkylamino side chain length and conformation: an NMR and ESR study. | 2009-09 |
|
| [5-(2-Fur-yl)-6-nitro-1,2,3,5,6,7-hexa-hydro-imidazo[1,2-a]pyridin-8-yl](phen-yl)methanone. | 2009-08-29 |
|
| Discovery of imidazo[1,2-a]pyridines as potent MCH1R antagonists. | 2009-08-15 |
|
| Orally active C-6 heteroaryl- and heterocyclyl-substituted imidazo[1,2-a]pyridine acid pump antagonists (APAs). | 2009-07-01 |
|
| 1-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-3,3-bis-(methyl-sulfan-yl)prop-2-enone monohydrate. | 2009-06-27 |
|
| Phosphonocarboxylates inhibit the second geranylgeranyl addition by Rab geranylgeranyl transferase. | 2009-03-13 |
|
| Discovery and optimization of imidazo[1,2-a]pyridine inhibitors of insulin-like growth factor-1 receptor (IGF-1R). | 2009-02-01 |
|
| DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: synthesis and antibacterial activity. | 2009-02-01 |
|
| IRAK-4 inhibitors for inflammation. | 2009 |
|
| Synthesis and anticandidal activity of some imidazopyridine derivatives. | 2008-12 |
|
| Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells. | 2008-11 |
|
| Synthesis and antituberculosis activity of new hydrazide derivatives. | 2008-11 |
|
| Novel imidazo[1,2-a]naphthyridinic systems (part 1): synthesis, antiproliferative and DNA-intercalating activities. | 2008-11 |
|
| IRAK-4 inhibitors. Part III: a series of imidazo[1,2-a]pyridines. | 2008-06-15 |
|
| IRAK-4 inhibitors. Part II: a structure-based assessment of imidazo[1,2-a]pyridine binding. | 2008-06-01 |
|
| 2-Phenyl-imidazo[1,2-a]pyridine-3-carbaldehyde. | 2008-04-26 |
|
| N-(2-Phenyl-imidazo[1,2-a]pyridin-3-yl)acetamide. | 2008-04-26 |
|
| Imidazo[1,2-a]pyridine derivatives as inhibitors of TNF-alpha expression in T cells. | 2008-02-01 |
|
| Switching of polymorph-dependent ESIPT luminescence of an imidazo[1,2-a]pyridine derivative. | 2008 |
|
| Diversification of the three-component coupling of 2-aminoheterocycles, aldehydes, and isonitriles: efficient parallel synthesis of a diverse and druglike library of imidazo- and tetrahydroimidazo[1,2-a] heterocycles. | 2007-09-11 |
|
| Synthesis and biological evaluation of sulfonylhydrazone-substituted imidazo[1,2-a]pyridines as novel PI3 kinase p110alpha inhibitors. | 2007-09-01 |
|
| Recent progress in the pharmacology of imidazo[1,2-a]pyridines. | 2007-09 |
|
| Synthesis and SAR studies of potent imidazopyridine anticoccidial agents. | 2007-07-01 |
|
| Efficient solid-phase synthesis of a library of imidazo[1,2-a]pyridine-8-carboxamides. | 2007-02-27 |
|
| Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110alpha inhibitors. | 2007-01-01 |
|
| A novel series of imidazo[1,2-a]pyridine derivatives as HIF-1alpha prolyl hydroxylase inhibitors. | 2006-11-01 |
|
| Synthesis and evaluation of two 18F-labeled imidazo[1,2-a]pyridine analogues as potential agents for imaging beta-amyloid in Alzheimer's disease. | 2006-06-01 |
|
| The cellular phenotype of AZ703, a novel selective imidazo[1,2-a]pyridine cyclin-dependent kinase inhibitor. | 2006-03 |
|
| AZ703, an imidazo[1,2-a]pyridine inhibitor of cyclin-dependent kinases 1 and 2, induces E2F-1-dependent apoptosis enhanced by depletion of cyclin-dependent kinase 9. | 2006-01-01 |
|
| Synthesis of indeno-fused derivatives of quinolizinium salts, imidazo[1,2-a]pyridine, pyrido[1,2-a]indole, and 4h-quinolizin-4-one via benzannulated enyne-allenes. | 2005-08-19 |
|
| Fused heterocycles: synthesis of some new imidazo[1,2-a]- pyridine derivatives. | 2004-09-30 |
|
| Identification of photoproducts from imazosulfuron by HPLC. | 2004-09 |
|
| Studies on the synthesis and characterization of four trans-planaramineplatinum(II) complexes of the form trans-PtL(NH3)CL2 where L = 2-hydroxypyridine, 3-hydroxypyridine, imidazole, and imidazo(1,2-alpha)pyridine. | 2004-08 |
|
| Phenylpiperazinylmethylheterocycle derivatives: synthesis and dopamine receptor binding profiles. | 2004-07 |
|
| Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors. | 2004-05-03 |
|
| Imidazo[1,2-a]pyridines. Part 2: SAR and optimisation of a potent and selective class of cyclin-dependent kinase inhibitors. | 2004-05-03 |
|
| Design and synthesis of acyclic nucleoside analogs with chlorinated imidazo[1,2-a]pyridine bases. | 2003-10 |
|
| Imidazo[1,2-a]pyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisation. | 2003-09-15 |
|
| Solid-phase synthesis of imidazo[1,2-a]pyridine using sodium benzenesulfinate as a traceless linker. | 2002-10-31 |
|
| Synthesis and biological evaluation of new imidazo[1,2-a]pyridine derivatives designed as mefloquine analogues. | 2002-10 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:51:12 GMT 2025
by
admin
on
Mon Mar 31 19:51:12 GMT 2025
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| Record UNII |
G18ZBV2HXA
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| Record Status |
Validated (UNII)
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| Record Version |
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