U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Fri Jun 25 21:36:10 UTC 2021
Edited
by admin
on Fri Jun 25 21:36:10 UTC 2021
Protein Sub Type
Sequence Type COMPLETE
Record UNII
G0D1L6VX5I
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NT-3 GROWTH FACTOR RECEPTOR
Common Name English
TRKC TYROSINE KINASE
Common Name English
NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 3
Common Name English
GP145-TRKC
Common Name English
TRK-C
Common Name English
TRKC
Common Name English
Code System Code Type Description
UNIPROT
Q16288
Created by admin on Fri Jun 25 21:36:10 UTC 2021 , Edited by admin on Fri Jun 25 21:36:10 UTC 2021
PRIMARY
FDA UNII
G0D1L6VX5I
Created by admin on Fri Jun 25 21:36:10 UTC 2021 , Edited by admin on Fri Jun 25 21:36:10 UTC 2021
PRIMARY
From To
1_289 1_331
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_41
N 1_48
N 1_102
N 1_132
N 1_172
N 1_187
N 1_201
N 1_228
N 1_236
N 1_241
N 1_263
N 1_344
N 1_357
Related Record Type Details
ACTIVATOR -> TARGET
INHIBITOR -> TARGET
IC50
INHIBITOR -> TARGET
INHIBITOR
IC50
INHIBITOR -> TARGET
Highly selective: limited inhibition of other kinases and >1,000x selective over other off targets
COMPETITIVE INHIBITOR
IC50
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL