Approval Year
Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 11:44:36 GMT 2023
by
admin
on
Sat Dec 16 11:44:36 GMT 2023
|
Protein Sub Type | |
Sequence Type | COMPLETE |
Record UNII |
G0D1L6VX5I
|
Record Status |
Validated (UNII)
|
Record Version |
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-
Download
Name | Type | Language | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
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Q16288
Created by
admin on Sat Dec 16 11:44:37 GMT 2023 , Edited by admin on Sat Dec 16 11:44:37 GMT 2023
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PRIMARY | |||
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G0D1L6VX5I
Created by
admin on Sat Dec 16 11:44:37 GMT 2023 , Edited by admin on Sat Dec 16 11:44:37 GMT 2023
|
PRIMARY |
From | To |
---|---|
1_289 | 1_331 |
Glycosylation Type | HUMAN |
Glycosylation Link Type | Site |
---|---|
N | 1_41 |
N | 1_48 |
N | 1_102 |
N | 1_132 |
N | 1_172 |
N | 1_187 |
N | 1_201 |
N | 1_228 |
N | 1_236 |
N | 1_241 |
N | 1_263 |
N | 1_344 |
N | 1_357 |
Related Record | Type | Details | ||
---|---|---|---|---|
|
ACTIVATOR -> TARGET | |||
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
Highly selective: limited inhibition of other kinases and >1,000x selective over other off targets
COMPETITIVE INHIBITOR
IC50
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
IC50
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RADIOLIGAND->TARGET |
Through a panel of 369 human kinases (no detectable kinase off-target at 1000-fold concentration over TrkB/C potency)
IC50
|
||
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INHIBITOR -> TARGET |
INHIBITOR
IC50
|
Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
---|---|---|---|---|---|---|
MOL_WEIGHT | CHEMICAL |
|