Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C5H9NO4 |
| Molecular Weight | 147.1293 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=O)OC[C@H](N)C(O)=O
InChI
InChIKey=VZXPDPZARILFQX-BYPYZUCNSA-N
InChI=1S/C5H9NO4/c1-3(7)10-2-4(6)5(8)9/h4H,2,6H2,1H3,(H,8,9)/t4-/m0/s1
| Molecular Formula | C5H9NO4 |
| Molecular Weight | 147.1293 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Mitochondrial serine acetyltransferase functions as a pacemaker of cysteine synthesis in plant cells. | 2008-10 |
|
| Comparative proteome analysis of secreted proteins of Streptococcus suis serotype 9 isolates from diseased and healthy pigs. | 2008-09 |
|
| Crystal structure of native O-acetyl-serine sulfhydrylase from Entamoeba histolytica and its complex with cysteine: structural evidence for cysteine binding and lack of interactions with serine acetyl transferase. | 2008-09 |
|
| Differential regulation of the expression of two high-affinity sulfate transporters, SULTR1.1 and SULTR1.2, in Arabidopsis. | 2008-06 |
|
| Metabolic pathways of the wheat (Triticum aestivum) endosperm amyloplast revealed by proteomics. | 2008-04-17 |
|
| Role of Histidine-152 in cofactor orientation in the PLP-dependent O-acetylserine sulfhydrylase reaction. | 2008-04-15 |
|
| Effect of mutation of lysine-120, located at the entry to the active site of O-acetylserine sulfhydrylase-A from Salmonella typhimurium. | 2008-04 |
|
| Kinetic characterization of methionine gamma-lyases from the enteric protozoan parasite Entamoeba histolytica against physiological substrates and trifluoromethionine, a promising lead compound against amoebiasis. | 2008-02 |
|
| The hidden universal distribution of amino acid biosynthetic networks: a genomic perspective on their origins and evolution. | 2008 |
|
| Rapid changes in gene expression dynamics in response to superoxide reveal SoxRS-dependent and independent transcriptional networks. | 2007-11-14 |
|
| Identification of intra- and intermolecular disulphide bonding in the plant mitochondrial proteome by diagonal gel electrophoresis. | 2007-11 |
|
| High resolution structure and catalysis of O-acetylserine sulfhydrylase isozyme B from Escherichia coli. | 2007-10 |
|
| Evaluation of the metal phytoextraction potential of crop legumes. Regulation of the expression of O-acetylserine (thiol)lyase under metal stress. | 2007-09 |
|
| Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis. Crystal structures of the enzyme alpha-aminoacrylate intermediate and an enzyme-inhibitor complex. | 2007-08-10 |
|
| Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: comparison of A and B isozymes. | 2007-07-17 |
|
| Crystallization and preliminary crystallographic analysis of cysteine synthase from Entamoeba histolytica. | 2007-06-01 |
|
| Multiple fungal enzymes possess cysteine synthase activity in vitro. | 2007-06 |
|
| Mutational analysis of O-acetylserine (thiol) lyase conducted in yeast two-hybrid system. | 2007-04 |
|
| Improving the nutritive value of tubers: elevation of cysteine and glutathione contents in the potato cultivar White Lady by marker-free transformation. | 2007-02-01 |
|
| Dominant-negative modification reveals the regulatory function of the multimeric cysteine synthase protein complex in transgenic tobacco. | 2007-02 |
|
| Cysteine biosynthesis in Trichomonas vaginalis involves cysteine synthase utilizing O-phosphoserine. | 2006-09-01 |
|
| Catalytic and regulatory properties of sulphur metabolizing enzymes in cyanobacterium Synechococcus elongatus PCC 7942. | 2006-09 |
|
| Sulphate assimilation under Cd2+ stress in Physcomitrella patens--combined transcript, enzyme and metabolite profiling. | 2006-09 |
|
| Identification, cloning and characterization of cysK, the gene encoding O-acetylserine (thiol)-lyase from Azospirillum brasilense, which is involved in tellurite resistance. | 2006-08 |
|
| Wheat EST resources for functional genomics of abiotic stress. | 2006-06-13 |
|
| Cloning, overexpression, purification, and characterization of O-acetylserine sulfhydrylase-B from Escherichia coli. | 2006-06 |
|
| On the interaction site of serine acetyltransferase in the cysteine synthase complex from Escherichia coli. | 2006-03-24 |
|
| Functional analysis of L-serine O-acetyltransferase from Corynebacterium glutamicum. | 2006-02 |
|
| Functional analysis of the cysteine synthase protein complex from plants: structural, biochemical and regulatory properties. | 2006-02 |
|
| Biochemical and functional characterization of phosphoserine aminotransferase from Entamoeba histolytica, which possesses both phosphorylated and non-phosphorylated serine metabolic pathways. | 2006-01 |
|
| Assessment of plants from the Brassicaceae family as genetic models for the study of nickel and zinc hyperaccumulation. | 2006 |
|
| Effects of simultaneous expression of heterologous genes involved in phytochelatin biosynthesis on thiol content and cadmium accumulation in tobacco plants. | 2006 |
|
| A three-dimensional homology model of the O-acetylserine sulfhydrylase-B from Salmonella typhimurium. | 2006 |
|
| Molecular basis of cysteine biosynthesis in plants: structural and functional analysis of O-acetylserine sulfhydrylase from Arabidopsis thaliana. | 2005-11-18 |
|
| Sulfur assimilation and glutathione metabolism under cadmium stress in yeast, protists and plants. | 2005-09 |
|
| Three-dimensional structure of a new enzyme, O-phosphoserine sulfhydrylase, involved in l-cysteine biosynthesis by a hyperthermophilic archaeon, Aeropyrum pernix K1, at 2.0A resolution. | 2005-08-12 |
|
| O-acetylserine (thiol) lyase activity in Phragmites and Typha plants under cadmium and NaCl stress conditions and the involvement of ABA in the stress response. | 2005-08 |
|
| Interaction of serine acetyltransferase with O-acetylserine sulfhydrylase active site: evidence from fluorescence spectroscopy. | 2005-08 |
|
| Elucidation of gene-to-gene and metabolite-to-gene networks in arabidopsis by integration of metabolomics and transcriptomics. | 2005-07-08 |
|
| N-terminal acetylation and protonation of individual hemoglobin subunits: position-dependent effects on tetramer strength and cooperativity. | 2005-06 |
|
| Impact of elevated H(2)S on metabolite levels, activity of enzymes and expression of genes involved in cysteine metabolism. | 2005-05 |
|
| Systems rebalancing of metabolism in response to sulfur deprivation, as revealed by metabolome analysis of Arabidopsis plants. | 2005-05 |
|
| O-acetylserine and the regulation of expression of genes encoding components for sulfate uptake and assimilation in potato. | 2005-05 |
|
| Mechanism of the addition half of the O-acetylserine sulfhydrylase-A reaction. | 2005-04-12 |
|
| Impact of reduced O-acetylserine(thiol)lyase isoform contents on potato plant metabolism. | 2005-03 |
|
| Molecular characterization of the CmbR activator-binding site in the metC-cysK promoter region in Lactococcus lactis. | 2005-02 |
|
| The serine acetyltransferase reaction: acetyl transfer from an acylpantothenyl donor to an alcohol. | 2005-01-01 |
|
| Isolation of Nicotiana plumbaginifolia cDNAs encoding isoforms of serine acetyltransferase and O-acetylserine (thiol) lyase in a yeast two-hybrid system with Escherichia coli cysE and cysK genes as baits. | 2005 |
|
| Production of nonproteinaceous amino acids using recombinant Escherichia coli cells expressing cysteine synthase and related enzymes with or without the secretion of O-acetyl-L-serine. | 2004 |
|
| Purification, characterization and gene cloning of thermostable O-acetyl-L-serine sulfhydrylase forming beta-cyano-L-alanine. | 2003 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 20:02:30 GMT 2025
by
admin
on
Mon Mar 31 20:02:30 GMT 2025
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| Record UNII |
G05L7T7ZEQ
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| Record Status |
Validated (UNII)
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| Record Version |
|
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Download
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Systematic Name | English | ||
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| Code System | Code | Type | Description | ||
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O-Acetylserine
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G05L7T7ZEQ
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DB01837
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DTXSID20904718
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99478
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5147-00-2
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58340
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17981
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226230
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