Arumakimig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 01:41:17 GMT 2025` Edited by `admin` on `Wed Apr 02 01:41:17 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	FWE2G0Y2W3
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MAS-825

Preferred Name

English

Arumakimig

Official Name

English

MAS825

Code

English

IgG-like bispecific monoclonal antibody (mAb) composed of the anti-IL-1beta mAb canakinumab and the anti-IL-18 mAb CMK389

Common Name

English

arumakimig [INN]

Common Name

English

immunoglobulin (H-gamma1_L-lambda2)_(H-gamma1_L-kappa), anti-[Homo sapiens IL18 (interleukin 18, IL-18, interferon gamma-inducing factor, IGIF, interleukin-1 gamma, IL-1G, IL1F4)] and anti-[Homo sapiens IL1B (interleukin 1 beta, IL-1B, 1L1F2)], Homo sapi

Common Name

English

MAS 825 [WHO-DD]

Common Name

English

BI-SPECIFIC HUMANIZED MONOCLONAL ANTIBODY AGAINST HUMAN IL-1.BETA. AND HUMAN IL-18

Common Name

English

H-gamma1 heavy chain anti-IL18 Homo sapiens (1-449) [VH (Homo sapiens IGHV1-69*01 (91.8%) -(IGHD) -IGHJ5*01 (92.9%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, 6-G1-v14 CH2 A1.3, A1.2, 14-G

Common Name

English

Immunoglobulin G1 [236-alanine,237-alanine,356-cysteine,368-tryptophan], anti-(human interleukin 18) (human monoclonal RITM5902350 ?1-chain), (222?215??)-disulfide with human monoclonal RITM5902350 ?2-chain, (228?227?),(231?230?),(356?350?)-tris(disulfid

Common Name

English

Code System Code Type Description

FDA UNII

FWE2G0Y2W3

Created by admin on Wed Apr 02 01:41:17 GMT 2025 , Edited by admin on Wed Apr 02 01:41:17 GMT 2025

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SMS_ID

300000026036

Created by admin on Wed Apr 02 01:41:17 GMT 2025 , Edited by admin on Wed Apr 02 01:41:17 GMT 2025

PRIMARY

INN

13493

Created by admin on Wed Apr 02 01:41:17 GMT 2025 , Edited by admin on Wed Apr 02 01:41:17 GMT 2025

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CAS

3018901-76-0

Created by admin on Wed Apr 02 01:41:17 GMT 2025 , Edited by admin on Wed Apr 02 01:41:17 GMT 2025

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From	To
1_22	1_96
1_146	1_202
1_222	2_215
1_263	1_323
1_228	3_227
1_231	3_230
1_356	3_350
1_369	1_427
2_22	2_89
2_138	2_197
3_22	3_96
3_145	3_201
3_221	4_214
3_262	3_322
3_368	3_426
4_23	4_88
4_134	4_194