U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula H3P
Molecular Weight 33.9976
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHOSPHINE

SMILES

P

InChI

InChIKey=XYFCBTPGUUZFHI-UHFFFAOYSA-N
InChI=1S/H3P/h1H3

HIDE SMILES / InChI

Molecular Formula H3P
Molecular Weight 33.9976
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Phosphine carries the chemical formula of PH3. The concentration of this compound constantly alters in our environment. Phosphine is an important agricultural fumigant with pulmonary and systemic toxicity that is generated on site as a gas given off by moisture coming in contact with solid form aluminum or zinc phosphide (e.g., in grain storage facilities or railway grain transport cars, where bystanders can be exposed). Phosphine also has industrial applications, particularly in the production of microelectronics. Symptoms such as diarrhea, nausea and vomiting, tightness of the chest, cough, headache, and dizziness have been reported in workers exposed intermittently to concentrations up to 35 ppm.

Approval Year

PubMed

PubMed

TitleDatePubMed
Chromosome rearrangements in fumigant appliers: possible relationship to non-Hodgkin's lymphoma risk.
1992 May-Jun
31Phosphorus magnetic resonance spectroscopy in late-onset Tay-Sachs disease.
2001 May
Association of polymorphic alleles of the calcium-sensing receptor gene with the clinical severity of primary hyperparathyroidism.
2001 Sep
Effects of PHEX antisense in human osteoblast cells.
2002 Feb
Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene.
2002 Feb
Calcification mimicking manganese-induced increased signal intensities in T1-weighted MR images in a patient taking herbal medicine: case report.
2003 Dec
Calcimimetic agents and secondary hyperparathyroidism: rationale for use and results from clinical trials.
2003 Dec
A case of oncogenic osteomalacia detected by 111In-pentetreotide total body scan.
2003 Jul-Aug
Major and trace elements in whole blood of phlebotomized patients with porphyria cutanea tarda.
2005
Increased parathyroid hormone gene expression in secondary hyperparathyroidism of experimental uremia is reversed by calcimimetics: correlation with posttranslational modification of the trans acting factor AUF1.
2006 Jan
Effects of the administration of corticosterone, parathyroid hormone, or both, and of their withdrawal, on rat bone and cartilage histomorphometric parameters, and on osteoprotegerin and RANKL mRNA expression and proteins.
2007 Jun
Elevated phosphorus modulates vitamin D receptor-mediated gene expression in human vascular smooth muscle cells.
2007 Nov
Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1alpha-hydroxylase expression in vitro.
2007 Nov
Phosphorous dysregulation induced by MEK small molecule inhibitors in the rat involves blockade of FGF-23 signaling in the kidney.
2012 Jan
Cholestatic presentation of yellow phosphorus poisoning.
2014 Jan
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 05:58:15 UTC 2023
Edited
by admin
on Sat Dec 16 05:58:15 UTC 2023
Record UNII
FW6947296I
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PHOSPHINE
HSDB   MI  
Systematic Name English
PHOSPHORUS HYDRIDE
Systematic Name English
HYDROGEN PHOSPHIDE
Common Name English
PHOSPHINE [HSDB]
Common Name English
PHOSPHINE [MI]
Common Name English
TK-GAS
Brand Name English
PHOSPHORUS TRIHYDRIDE
Systematic Name English
PHOSPHINE (PH3)
Common Name English
VAPORPHOS
Brand Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 66500
Created by admin on Sat Dec 16 05:58:15 UTC 2023 , Edited by admin on Sat Dec 16 05:58:15 UTC 2023
Code System Code Type Description
MESH
C044646
Created by admin on Sat Dec 16 05:58:15 UTC 2023 , Edited by admin on Sat Dec 16 05:58:15 UTC 2023
PRIMARY
ECHA (EC/EINECS)
232-260-8
Created by admin on Sat Dec 16 05:58:15 UTC 2023 , Edited by admin on Sat Dec 16 05:58:15 UTC 2023
PRIMARY
ALANWOOD
phosphine
Created by admin on Sat Dec 16 05:58:15 UTC 2023 , Edited by admin on Sat Dec 16 05:58:15 UTC 2023
PRIMARY
PUBCHEM
24404
Created by admin on Sat Dec 16 05:58:15 UTC 2023 , Edited by admin on Sat Dec 16 05:58:15 UTC 2023
PRIMARY
FDA UNII
FW6947296I
Created by admin on Sat Dec 16 05:58:15 UTC 2023 , Edited by admin on Sat Dec 16 05:58:15 UTC 2023
PRIMARY
MERCK INDEX
m8720
Created by admin on Sat Dec 16 05:58:15 UTC 2023 , Edited by admin on Sat Dec 16 05:58:15 UTC 2023
PRIMARY Merck Index
CHEBI
30278
Created by admin on Sat Dec 16 05:58:15 UTC 2023 , Edited by admin on Sat Dec 16 05:58:15 UTC 2023
PRIMARY
CAS
7803-51-2
Created by admin on Sat Dec 16 05:58:15 UTC 2023 , Edited by admin on Sat Dec 16 05:58:15 UTC 2023
PRIMARY
EPA CompTox
DTXSID2021157
Created by admin on Sat Dec 16 05:58:15 UTC 2023 , Edited by admin on Sat Dec 16 05:58:15 UTC 2023
PRIMARY
WIKIPEDIA
PHOSPHINE
Created by admin on Sat Dec 16 05:58:15 UTC 2023 , Edited by admin on Sat Dec 16 05:58:15 UTC 2023
PRIMARY
HSDB
1233
Created by admin on Sat Dec 16 05:58:15 UTC 2023 , Edited by admin on Sat Dec 16 05:58:15 UTC 2023
PRIMARY