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Details

Stereochemistry MIXED
Molecular Formula C20H33NO3.ClH
Molecular Weight 371.942
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GANGLEFENE HYDROCHLORIDE

SMILES

Cl.CCN(CC)CC(C)C(C)OC(=O)C1=CC=C(OCC(C)C)C=C1

InChI

InChIKey=XVCRYGWPPJRQJP-UHFFFAOYSA-N
InChI=1S/C20H33NO3.ClH/c1-7-21(8-2)13-16(5)17(6)24-20(22)18-9-11-19(12-10-18)23-14-15(3)4;/h9-12,15-17H,7-8,13-14H2,1-6H3;1H

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C20H33NO3
Molecular Weight 335.4809
Charge 0
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description
Curator's Comment: No abstract or full text available for the following articles: https://europepmc.org/abstract/med/13486531 | https://europepmc.org/abstract/med/13550627

Ganglefene is a coronary vasodilator. This n-cholinoblocker was originally studied for its effects on coronary circulation in angina pectoris. Animal studies have also shown shortened recovery period of motor functions after ganglefene administration. One rodent study showed that modulation of the n-cholinergic system by ganglefene in the developing fetal brain leads to changes in the quantitative and qualitative characteristics of elements of sexual behavior in pubescent offspring.

Approval Year

Unknown
149124
Substance Class Chemical
Created
by admin
on Tue Apr 01 20:50:50 GMT 2025
Edited
by admin
on Tue Apr 01 20:50:50 GMT 2025
Record UNII
FW5QT31LI6
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GANGLEFENE HYDROCHLORIDE
Common Name English
2-BUTANOL, 4-(DIETHYLAMINO)-3-METHYL-, P-ISOBUTOXYBENZOATE (ESTER), HYDROCHLORIDE
Preferred Name English
BENZOIC ACID, P-ISOBUTOXY-, 3-(DIETHYLAMINO)-1,2-DIMETHYLPROPYL ESTER HYDROCHLORIDE
Systematic Name English
OXYCAINE 12
Common Name English
.ALPHA.,.BETA.-DIMETHYL-.GAMMA.-(DIETHYLAMINO)PROPYL P-ISOBUTOXYBENZOATE HYDROCHLORIDE
Systematic Name English
BENZOIC ACID, 4-(2-METHYLPROPOXY)-, 3-(DIETHYLAMINO)-1,2-DIMETHYLPROPYL ESTER, HYDROCHLORIDE (1:1)
Systematic Name English
3-DIETHYLAMINO-1,2-DIMETHYLPROPYL P-ISOBUTOXYBENZOATE HYDROCHLORIDE
Systematic Name English
GANGLERONE
Common Name English
Ganglefene hydrochloride [WHO-DD]
Common Name English
GANGLEXON HYDROCHLORIDE
Common Name English
GANGLERON HYDROCHLORIDE
Common Name English
BENZOIC ACID, 4-(2-METHYLPROPOXY)-, 3-(DIETHYLAMINO)-1,2-DIMETHYLPROPYL ESTER, HYDROCHLORIDE
Systematic Name English
GANGLERON
Common Name English
Code System Code Type Description
SMS_ID
100000183702
Created by admin on Tue Apr 01 20:50:50 GMT 2025 , Edited by admin on Tue Apr 01 20:50:50 GMT 2025
PRIMARY
CAS
1510-29-8
Created by admin on Tue Apr 01 20:50:50 GMT 2025 , Edited by admin on Tue Apr 01 20:50:50 GMT 2025
PRIMARY
PUBCHEM
134483
Created by admin on Tue Apr 01 20:50:50 GMT 2025 , Edited by admin on Tue Apr 01 20:50:50 GMT 2025
PRIMARY
FDA UNII
FW5QT31LI6
Created by admin on Tue Apr 01 20:50:50 GMT 2025 , Edited by admin on Tue Apr 01 20:50:50 GMT 2025
PRIMARY
EPA CompTox
DTXSID70934146
Created by admin on Tue Apr 01 20:50:50 GMT 2025 , Edited by admin on Tue Apr 01 20:50:50 GMT 2025
PRIMARY
NIH
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