U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
139594
Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 16:49:59 UTC 2023
Edited
by admin
on Sat Dec 16 16:49:59 UTC 2023
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE GENETICALLY MODIFIED
Organism Family Adenoviridae
Organism Genus Mastadenovirus
Organism Species human mastadenovirus c
Infraspecific Type SUBSTRAIN
Infraspecific Name OBP-301
Part whole
Record UNII
FV0JG1SX76
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Suratadenoturev
USAN   INN  
Official Name English
DNA (recombinant human telomerase-specific replication-competent oncolytic adenovirus 5 vector OBP-301)
Common Name English
OBP-301
Code English
A recombinant replication-competent adenovirus type 5 (Ad-5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and replaced by an expression cassette containing an hTERT (human telomerase reverse transcriptas
Common Name English
Suratadenoturev [WHO-DD]
Common Name English
TELOMELYSIN
Common Name English
A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human telomerase reverse transcriptase (hTERT) and IRES, respectively.
Common Name English
suratadenoturev [INN]
Common Name English
SURATADENOTUREV [USAN]
Common Name English
Code System Code Type Description
NCI_THESAURUS
C119617
Created by admin on Sat Dec 16 16:49:59 UTC 2023 , Edited by admin on Sat Dec 16 16:49:59 UTC 2023
PRIMARY
USAN
LM-80
Created by admin on Sat Dec 16 16:49:59 UTC 2023 , Edited by admin on Sat Dec 16 16:49:59 UTC 2023
PRIMARY
INN
11484
Created by admin on Sat Dec 16 16:49:59 UTC 2023 , Edited by admin on Sat Dec 16 16:49:59 UTC 2023
PRIMARY
CAS
1160991-31-0
Created by admin on Sat Dec 16 16:49:59 UTC 2023 , Edited by admin on Sat Dec 16 16:49:59 UTC 2023
NO STRUCTURE GIVEN
CAS
1268642-13-2
Created by admin on Sat Dec 16 16:49:59 UTC 2023 , Edited by admin on Sat Dec 16 16:49:59 UTC 2023
PRIMARY
FDA UNII
FV0JG1SX76
Created by admin on Sat Dec 16 16:49:59 UTC 2023 , Edited by admin on Sat Dec 16 16:49:59 UTC 2023
PRIMARY
Related Record Type Details
Suratadenoturev
ACTIVE MOIETY
This has capacity to selectively replicate in tumor cell and inhibit tumor cell growth.

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
TRANSGENE SURATADENOTUREV GENE INSERT A66I7XQ66A
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966