TETRALIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H12
Molecular Weight	132.2023
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C1CCC2=CC=CC=C2C1

InChI

InChIKey=CXWXQJXEFPUFDZ-UHFFFAOYSA-N

InChI=1S/C10H12/c1-2-6-10-8-4-3-7-9(10)5-1/h1-2,5-6H,3-4,7-8H2

HIDE SMILES / InChI

Molecular Formula	C10H12
Molecular Weight	132.2023
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Conformationally constrained analogues of N'-(4-tert-butylbenzyl)-N-(4-methylsulfonylaminobenzyl)thiourea as TRPV1 antagonists.	2009-01	18406014
Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials.	2009-01	18313805
Aryl 4,6-O-arylidene-1-thio-beta-d-glycopyranoside-based new organogelators and their gels.	2008-10-13	18619583
Controllable one-step synthesis of spirocycles, polycycles, and di- and tetrahydronaphthalenes from aryl-substituted propargylic alcohols.	2008-09-05	18681405
Investigations of the growth kinetics of capped CdSe and CdS nanocrystals by a combined use of small angle X-ray scattering and other techniques.	2008-09-01	18637656
Metabolism, distribution, and excretion of a next generation selective estrogen receptor modulator, lasofoxifene, in rats and monkeys.	2008-09	18515329
Tandem Friedel-Crafts annulation to novel perylene analogues.	2008-08-15	18630879
Disposition of lasofoxifene, a next-generation selective estrogen receptor modulator, in healthy male subjects.	2008-07	18372400
Styrene trimer may increase thyroid hormone levels via down-regulation of the aryl hydrocarbon receptor (AhR) target gene UDP-glucuronosyltransferase.	2008-06	18560529
5-HT1A/7 receptor agonist excites cardiac vagal neurons via inhibition of both GABAergic and glycinergic inputs.	2008-05	18430360
Microwave-mediated nickel-catalyzed cyclotrimerization reactions: total synthesis of illudinine.	2008-01-04	18052296
Small P-gp modulating molecules: SAR studies on tetrahydroisoquinoline derivatives.	2008-01-01	17936633
Is the Hoveyda-Grubbs complex a vinylogous Fischer-type carbene? Aromaticity-controlled activity of ruthenium metathesis catalysts.	2008	18770510
Thermal diffusion forced Rayleigh scattering setup optimized for aqueous mixtures.	2007-12-27	18052276
Nonsteroidal glucocorticoid agonists: tetrahydronaphthalenes with alternative steroidal A-ring mimetics possessing dissociated (transrepression/transactivation) efficacy selectivity.	2007-12-27	18038970
Determination of total biodiesel fatty acid methyl, ethyl esters, and hydrocarbon types in diesel fuels by supercritical fluid chromatography-flame ionization detection.	2007-12-15	18078578
Construction of a chiral central nervous system (CNS)-active aminotetralin drug compound based on a synthesis strategy using multitasking properties of (S)-1-phenylethylamine.	2007-12	17668920
Structure investigation of sertraline drug and its iodine product using mass spectrometry, thermal analyses and MO-calculations.	2007-11	17368086
Silicon analogues of the retinoid agonists TTNPB and 3-methyl-TTNPB, disila-TTNPB and disila-3-methyl-TTNPB: chemistry and biology.	2007-09-24	17768726
Non-steroidal glucocorticoid agonists: the discovery of aryl pyrazoles as A-ring mimetics.	2007-09-01	17616395
Fluorescence and ultraviolet absorption spectra, and the structure and vibrations of 1,2,3,4-tetrahydronaphthalene in its S1(pi,pi*) state.	2007-08-30	17685499
Disila-okoumal: a silicon analogue of the ambergris odorant okoumal.	2007-08-13	17616951
Optical cell with periodic resistive heating for the measurement of heat, mass, and thermal diffusions in liquid mixtures.	2007-08	17764346
Biomass in the manufacture of industrial products--the use of proteins and amino acids.	2007-06	17387469
Reductive hydrogenation of polycyclic aromatic hydrocarbons catalyzed by metalloporphyrins.	2007-06	17335868
Synthesis of daunorubicin analogues containing truncated aromatic cores and unnatural monosaccharide residues.	2007-04-13	17373847
A novel, non-substrate-based series of glycine type 1 transporter inhibitors derived from high-throughput screening.	2007-03-15	17257843
Discovery of tetralin ureas as potent melanin concentrating hormone 1 receptor antagonists.	2007-03-15	17251014
Role of serotonin-1A receptors in restraint-induced behavioral deficits and adaptation to repeated restraint stress in rats.	2007-02	17365111
Naphthalocyanine-reconstituted LDL nanoparticles for in vivo cancer imaging and treatment.	2007	18203443
Phenylazo-pyridine and phenylazo-pyrazole chlorido ruthenium(II) arene complexes: arene loss, aquation, and cancer cell cytotoxicity.	2006-12-25	17173447
Podophyllum hexandrum Offers Radioprotection by Modulating Free Radical Flux: Role of Aryl-Tetralin Lignans.	2006-12	17173115
TP receptor as a therapeutic target in atherosclerosis and related cardiovascular diseases.	2006-11	18221089
Development of supercritical fluid extraction coupled to comprehensive two-dimensional supercritical fluid chromatography (SFE-SFCxSFC).	2006-11	17099275
Monocyclic and dicyclic hydrocarbons: structural requirements for proximal giant axonopathy.	2006-09	16874529
Design, synthesis, and biochemical evaluation of novel cruzain inhibitors with potential application in the treatment of Chagas' disease.	2006-08-15	16781147
Dissociated nonsteroidal glucocorticoid receptor modulators; discovery of the agonist trigger in a tetrahydronaphthalene-benzoxazine series.	2006-07-13	16821781
Design and synthesis of an alpha1a-adrenergic receptor subtype-selective antagonist from BE2254.	2006-06	16882319
Alternative procedure for the synthesis of Mansonone F and Biflorin precursor.	2006-05-20	16835097
Synthesis and anticonvulsant activity of a class of 2-amino 3-hydroxypropanamide and 2-aminoacetamide derivatives.	2006-05-15	16460950
An intramolecular substitution of hydroperoxy-endoperoxide to a bis-endoperoxide.	2006-04-27	16623552
The endophytic fungus Trametes hirsuta as a novel alternative source of podophyllotoxin and related aryl tetralin lignans.	2006-04-20	16375985
A new class of bradykinin 1 receptor antagonists containing the piperidine acetic acid tetralin core.	2006-04-15	16464576
Proteomic and transcriptional characterization of aromatic degradation pathways in Rhodoccocus sp. strain TFB.	2006-04	16544280
Major congenital malformations and residential proximity to a regional industrial park including a national toxic waste site: an ecological study.	2006-03-29	16571107
Designing rapid onset selective serotonin re-uptake inhibitors. Part 1: Structure-activity relationships of substituted (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthaleneamine.	2006-03-01	16314097
Hydrovinylation of 1,3-dienes: a new protocol, an asymmetric variation, and a potential solution to the exocyclic side chain stereochemistry problem.	2006-01-11	16390118
Self-depletion flocculation of tetralin oil-in-water emulsions.	2006-01-03	16378404
Cardiovascular effects of KUR-1246, a new tetrahydronaphthalen derivative beta2-adrenoceptor agonist and a selective uterine relaxant.	2006	16478001
DFT-GIAO study of aryltetralin lignan lactones: conformational analyses and chemical shifts calculations.	2005-12	16289684

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:53:51 GMT 2025` Edited by `admin` on `Mon Mar 31 18:53:51 GMT 2025`
Record UNII	FT6XMI58YQ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TETRALIN

Systematic Name

English

NSC-77451

Preferred Name

English

Tetralin [WHO-DD]

Common Name

English

TETRALIN [HSDB]

Common Name

English

TETRALIN [MI]

Common Name

English

TETRALIN [USP-RS]

Common Name

English

TETRANAP

Common Name

English

1,2,3,4-TETRAHYDRONAPHTHALENE

Systematic Name

English

Code System Code Type Description

MESH

C095210