Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C18H20ClN3O.ClH.H2O |
| Molecular Weight | 384.3 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.Cl.CN(C)CCCN1C(=O)N(C2=C1C=CC(Cl)=C2)C3=CC=CC=C3
InChI
InChIKey=KUSWMSGQGZMJGX-UHFFFAOYSA-N
InChI=1S/C18H20ClN3O.ClH.H2O/c1-20(2)11-6-12-21-16-10-9-14(19)13-17(16)22(18(21)23)15-7-4-3-5-8-15;;/h3-5,7-10,13H,6,11-12H2,1-2H3;1H;1H2
| Molecular Formula | H2O |
| Molecular Weight | 18.0153 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C18H20ClN3O |
| Molecular Weight | 329.824 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Clodazon (AW 142446) is an antidepressant drug investigated in Germany in the 1960s. In animal models, clodazon inhibits the catalepsy induced by tetrabenazine and it potentiates the effect of catecholamines, both effects being of the order experienced with imipramine. In clinical trials, about 2/3 of the patients showed a positive antidepressive effect with few side effects.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:31:50 GMT 2025
by
admin
on
Mon Mar 31 18:31:50 GMT 2025
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| Record UNII |
FSF9L5AH4G
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C265
Created by
admin on Mon Mar 31 18:31:50 GMT 2025 , Edited by admin on Mon Mar 31 18:31:50 GMT 2025
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| Code System | Code | Type | Description | ||
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FSF9L5AH4G
Created by
admin on Mon Mar 31 18:31:50 GMT 2025 , Edited by admin on Mon Mar 31 18:31:50 GMT 2025
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PRIMARY | |||
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DTXSID40185789
Created by
admin on Mon Mar 31 18:31:50 GMT 2025 , Edited by admin on Mon Mar 31 18:31:50 GMT 2025
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CHEMBL2110801
Created by
admin on Mon Mar 31 18:31:50 GMT 2025 , Edited by admin on Mon Mar 31 18:31:50 GMT 2025
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PRIMARY | |||
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167451
Created by
admin on Mon Mar 31 18:31:50 GMT 2025 , Edited by admin on Mon Mar 31 18:31:50 GMT 2025
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PRIMARY | |||
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C78012
Created by
admin on Mon Mar 31 18:31:50 GMT 2025 , Edited by admin on Mon Mar 31 18:31:50 GMT 2025
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31959-88-3
Created by
admin on Mon Mar 31 18:31:50 GMT 2025 , Edited by admin on Mon Mar 31 18:31:50 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ANHYDROUS->SOLVATE | |||
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PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |