U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:09:31 GMT 2023
Edited
by admin
on Sat Dec 16 15:09:31 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
FR57BKG0QJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Cepeprubart
INN  
Official Name English
ANTI-PSGL-1 ANTIBODY SELK2
Common Name English
Immunoglobulin G2, anti-(human CD162 antigen) (human-Mus musculus monoclonal SelK2 γ2-chain), disulfide with human-Mus musculus monoclonal SelK2 κ-chain, dimer
Common Name English
Immunoglobulin G2-kappa, anti-[Homo sapiens SELPLG (selectin P ligand, PSGL-1, P-selectin glycoprotein ligand 1, CD162)], monoclonal antibody
Common Name English
cepeprubart [INN]
Common Name English
SELK2
Common Name English
Gamma2 heavy chain (1-439) [VH (Homo sapiens IGHV3-30*03(91.8%) -(IGHD) -IGHJ5*02 (100%) , CDR-IMGT [8.8.6] (26-33.51-58.97-102)) (1-113) -Homo sapiens IGHG2*02, G2m23 CH2 M45.1, A105 (CH1 (114-211), hinge 1-12 (212-223), CH2 M45.1 (274),K105>A (314) (22
Common Name English
Code System Code Type Description
CAS
2769758-59-8
Created by admin on Sat Dec 16 15:09:31 GMT 2023 , Edited by admin on Sat Dec 16 15:09:31 GMT 2023
PRIMARY
INN
12715
Created by admin on Sat Dec 16 15:09:31 GMT 2023 , Edited by admin on Sat Dec 16 15:09:31 GMT 2023
PRIMARY
FDA UNII
FR57BKG0QJ
Created by admin on Sat Dec 16 15:09:31 GMT 2023 , Edited by admin on Sat Dec 16 15:09:31 GMT 2023
PRIMARY
From To
1_22 1_96
1_359 1_417
2_22 2_96
2_127 4_219
2_140 2_196
1_127 3_219
2_253 2_313
2_359 2_417
3_23 3_93
3_139 3_199
1_140 1_196
4_23 4_93
4_139 4_199
1_215 2_215
1_216 2_216
1_219 2_219
1_222 2_222
1_253 1_313
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_289
N 2_289
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL