6-Hydroxydopa hydrochloride , DL-

Cl.NC(CC1=C(O)C=C(O)C(O)=C1)C(O)=O

InChIKey=BFABEGDECPTTRS-UHFFFAOYSA-N

InChI=1S/C9H11NO5.ClH/c10-5(9(14)15)1-4-2-7(12)8(13)3-6(4)11;/h2-3,5,11-13H,1,10H2,(H,14,15);1H

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
DNA-(apurinic or apyrimidinic site) lyase 8 Target ID: CHEMBL5619 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20809131 \| https://www.ncbi.nlm.nih.gov/pubmed/19484131	Inhibitor 8297		0.11 µM [IC50]
DNA repair protein RAD52 homolog 2 Target ID: CHEMBL2362978 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26548611	Inhibitor 8297		1.1 µM [IC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 20:17:56 UTC 2023` Edited by `admin` on `Sat Dec 16 20:17:56 UTC 2023`
Record UNII	FQJ6LEK5R9
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

6-Hydroxydopa hydrochloride , DL-

Common Name

English

Tyrosine, 2,5-dihydroxy-, hydrochloride

Systematic Name

English

Code System Code Type Description

PUBCHEM

168441272

Created by admin on Sat Dec 16 20:17:56 UTC 2023 , Edited by admin on Sat Dec 16 20:17:56 UTC 2023

PRIMARY

FDA UNII

FQJ6LEK5R9

Created by admin on Sat Dec 16 20:17:56 UTC 2023 , Edited by admin on Sat Dec 16 20:17:56 UTC 2023

PRIMARY

CAS

68463-64-9

Created by admin on Sat Dec 16 20:17:56 UTC 2023 , Edited by admin on Sat Dec 16 20:17:56 UTC 2023

PRIMARY

Related Record Type Details


					9HBL9XYQ8O

PARENT -> SALT/SOLVATE

Amount: