| Stereochemistry | ACHIRAL |
| Molecular Formula | C15H12Br4O2 |
| Molecular Weight | 543.871 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(C1=CC(Br)=C(O)C(Br)=C1)C2=CC(Br)=C(O)C(Br)=C2
InChI
InChIKey=VEORPZCZECFIRK-UHFFFAOYSA-N
InChI=1S/C15H12Br4O2/c1-15(2,7-3-9(16)13(20)10(17)4-7)8-5-11(18)14(21)12(19)6-8/h3-6,20-21H,1-2H3
| Molecular Formula | C15H12Br4O2 |
| Molecular Weight | 543.871 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effects of the environmental oestrogens bisphenol A, tetrachlorobisphenol A, tetrabromobisphenol A, 4-hydroxybiphenyl and 4,4'-dihydroxybiphenyl on oestrogen receptor binding, cell proliferation and regulation of oestrogen sensitive proteins in the human breast cancer cell line MCF-7. | 2003 Apr |
|
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006 Nov |
|
| Molecular targets of TBBPA in zebrafish analysed through integration of genomic and proteomic approaches. | 2008 Dec |
|
| Effects of fifteen PBDE metabolites, DE71, DE79 and TBBPA on steroidogenesis in the H295R cell line. | 2008 May |
|
| Risk assessment of tetrabromobisphenol A on cyclooxygenase-2 expression via MAP kinase/NF-kappaB/AP-1 signaling pathways in murine macrophages. | 2009 |
|
| Some commonly used brominated flame retardants cause Ca2+-ATPase inhibition, beta-amyloid peptide release and apoptosis in SH-SY5Y neuronal cells. | 2012 |
|
| Disruption of the hypothalamic-pituitary-thyroid axis in zebrafish embryo-larvae following waterborne exposure to BDE-47, TBBPA and BPA. | 2012 Feb |
|
| An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide. | 2012 Jan 5 |
|
| Tetrabromobisphenol-A disrupts thyroid hormone receptor alpha function in vitro: use of fluorescence polarization to assay corepressor and coactivator peptide binding. | 2012 May |
|
| Endocrine disruptors differentially target ATP-binding cassette transporters in the blood-testis barrier and affect Leydig cell testosterone secretion in vitro. | 2013 Dec |
|
| In vitro study on the agonistic and antagonistic activities of bisphenol-S and other bisphenol-A congeners and derivatives via nuclear receptors. | 2013 Oct 1 |
|
| Comparative antioxidant status in freshwater fish Carassius auratus exposed to six current-use brominated flame retardants: a combined experimental and theoretical study. | 2013 Sep 15 |
|
| PBDE: structure-activity studies for the inhibition of hepatitis C virus NS3 helicase. | 2014 Apr 2 |
|
| Halogenated bisphenol-A analogs act as obesogens in zebrafish larvae (Danio rerio). | 2014 May |
|
| Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently. | 2015 Apr 1 |
|
| Structurally-diverse, PPARγ-activating environmental toxicants induce adipogenesis and suppress osteogenesis in bone marrow mesenchymal stromal cells. | 2015 May 4 |
Patents
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
6618 | PRIMARY | |||
|
33217 | PRIMARY | |||
|
TETRABROMOBISPHENOL A | PRIMARY | |||
|
5232 | PRIMARY | |||
|
DTXSID1026081 | PRIMARY | |||
|
FQI02RFC3A | PRIMARY | |||
|
79-94-7 | PRIMARY | |||
|
201-236-9 | PRIMARY | |||
|
59775 | PRIMARY | |||
|
C020806 | PRIMARY | |||
|
m10598 | PRIMARY | Merck Index |