Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C15H12Br4O2 |
| Molecular Weight | 543.871 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(C1=CC(Br)=C(O)C(Br)=C1)C2=CC(Br)=C(O)C(Br)=C2
InChI
InChIKey=VEORPZCZECFIRK-UHFFFAOYSA-N
InChI=1S/C15H12Br4O2/c1-15(2,7-3-9(16)13(20)10(17)4-7)8-5-11(18)14(21)12(19)6-8/h3-6,20-21H,1-2H3
| Molecular Formula | C15H12Br4O2 |
| Molecular Weight | 543.871 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Potent competitive interactions of some brominated flame retardants and related compounds with human transthyretin in vitro. | 2000 Jul |
|
| Estrogen-like properties of brominated analogs of bisphenol A in the MCF-7 human breast cancer cell line. | 2001 |
|
| Brominated dioxin-like compounds: in vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds. | 2003 Sep |
|
| Effects of tetrabromobisphenol A, brominated flame retardant, in ICR mice after prenatal and postnatal exposure. | 2006 Aug |
|
| Biosensor recognition of thyroid-disrupting chemicals using transport proteins. | 2006 Feb 15 |
|
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006 Nov |
|
| Cytotoxicity of TBBPA and effects on proliferation, cell cycle and MAPK pathways in mammalian cells. | 2007 Apr |
|
| Molecular targets of TBBPA in zebrafish analysed through integration of genomic and proteomic approaches. | 2008 Dec |
|
| Tetrabromobisphenol A (TBBPA), induces cell death in TM4 Sertoli cells by modulating Ca2+ transport proteins and causing dysregulation of Ca2+ homeostasis. | 2008 Jun |
|
| Risk assessment of tetrabromobisphenol A on cyclooxygenase-2 expression via MAP kinase/NF-kappaB/AP-1 signaling pathways in murine macrophages. | 2009 |
|
| Assessing the toxicity of TBBPA and HBCD by zebrafish embryo toxicity assay and biomarker analysis. | 2009 Aug |
|
| Some flame retardants and the antimicrobials triclosan and triclocarban enhance the androgenic activity in vitro. | 2010 Nov |
|
| Molecular Mechanism of Tetrabromobisphenol A (TBBPA)-induced Target Organ Toxicity in Sprague-Dawley Male Rats. | 2011 Jun |
|
| Parallel biotransformation of tetrabromobisphenol A in Xenopus laevis and mammals: Xenopus as a model for endocrine perturbation studies. | 2012 Feb |
|
| An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide. | 2012 Jan 5 |
|
| Multiple novel modes of action involved in the in vitro neurotoxic effects of tetrabromobisphenol-A. | 2012 Jul |
|
| Brominated flame retardants stimulate mouse immune cells in vitro. | 2013 Dec |
|
| Effect of tetrabrombisphenol A on induction of apoptosis in the testes and changes in expression of selected testicular genes in CD1 mice. | 2013 Jan |
|
| Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity. | 2013 Jun |
|
| Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently. | 2015 Apr 1 |
|
| Structural bisphenol analogues differentially target steroidogenesis in murine MA-10 Leydig cells as well as the glucocorticoid receptor. | 2015 Mar 2 |
|
| Advanced morphological - behavioral test platform reveals neurodevelopmental defects in embryonic zebrafish exposed to comprehensive suite of halogenated and organophosphate flame retardants. | 2015 May |
|
| Structurally-diverse, PPARγ-activating environmental toxicants induce adipogenesis and suppress osteogenesis in bone marrow mesenchymal stromal cells. | 2015 May 4 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:41:25 GMT 2023
by
admin
on
Fri Dec 15 18:41:25 GMT 2023
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| Record UNII |
FQI02RFC3A
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| Record Status |
Validated (UNII)
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| Record Version |
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TETRABROMOBISPHENOL A
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C020806
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m10598
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