MANFIDOKIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 22:45:48 GMT 2025` Edited by `admin` on `Tue Apr 01 22:45:48 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	FQ7M3IAT8U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IMMUNOGLOBULIN G4 (224-PROLINE), ANTI-(HUMAN INTERLEUKIN 4 RECEPTOR SUBUNIT .ALPHA.) (HUMAN-MUS MUSCULUS MONOCLONAL AK120 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL AK120 .KAPPA.-CHAIN, DIMER

Preferred Name

English

MANFIDOKIMAB

Official Name

English

Manfidokimab [WHO-DD]

Common Name

English

manfidokimab [INN]

Common Name

English

Code System Code Type Description

FDA UNII

FQ7M3IAT8U

Created by admin on Tue Apr 01 22:45:48 GMT 2025 , Edited by admin on Tue Apr 01 22:45:48 GMT 2025

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INN

11811

Created by admin on Tue Apr 01 22:45:48 GMT 2025 , Edited by admin on Tue Apr 01 22:45:48 GMT 2025

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NCI_THESAURUS

C184866

Created by admin on Tue Apr 01 22:45:48 GMT 2025 , Edited by admin on Tue Apr 01 22:45:48 GMT 2025

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CAS

2428381-56-8

Created by admin on Tue Apr 01 22:45:48 GMT 2025 , Edited by admin on Tue Apr 01 22:45:48 GMT 2025

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SMS_ID

300000039125

Created by admin on Tue Apr 01 22:45:48 GMT 2025 , Edited by admin on Tue Apr 01 22:45:48 GMT 2025

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From	To
1_22	1_96
2_22	2_96
2_130	4_214
2_143	2_199
2_257	2_317
1_130	3_214
2_363	2_421
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_143	1_199
1_222	2_222
1_225	2_225
1_257	1_317
1_363	1_421

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_293
N	2_293

Related Record Type Details


					2HR7ATK059

INTERLEUKIN-4 RECEPTOR SUBUNIT ALPHA

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					FQ7M3IAT8U

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION					PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL	[1_443] [2_443]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL