U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 17:27:42 GMT 2023
Edited
by admin
on Sat Dec 16 17:27:42 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
FPW3780T3E
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SETRUSUMAB
INN  
Official Name English
BPS804
Code English
MOR05813
Code English
setrusumab [INN]
Common Name English
BPS-804
Code English
Setrusumab [WHO-DD]
Common Name English
IMMUNOGLOBULIN G2, ANTI-(HUMAN SCLEROSTIN) (HUMAN MONOCLONAL BPS804 HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL BPS804 LIGHT CHAIN, DIMER
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C78281
Created by admin on Sat Dec 16 17:27:42 GMT 2023 , Edited by admin on Sat Dec 16 17:27:42 GMT 2023
FDA ORPHAN DRUG 508615
Created by admin on Sat Dec 16 17:27:42 GMT 2023 , Edited by admin on Sat Dec 16 17:27:42 GMT 2023
NCI_THESAURUS C20401
Created by admin on Sat Dec 16 17:27:42 GMT 2023 , Edited by admin on Sat Dec 16 17:27:42 GMT 2023
EU-Orphan Drug EU/3/16/1686
Created by admin on Sat Dec 16 17:27:42 GMT 2023 , Edited by admin on Sat Dec 16 17:27:42 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C152352
Created by admin on Sat Dec 16 17:27:42 GMT 2023 , Edited by admin on Sat Dec 16 17:27:42 GMT 2023
PRIMARY
CAS
1847394-95-9
Created by admin on Sat Dec 16 17:27:42 GMT 2023 , Edited by admin on Sat Dec 16 17:27:42 GMT 2023
PRIMARY
INN
10539
Created by admin on Sat Dec 16 17:27:42 GMT 2023 , Edited by admin on Sat Dec 16 17:27:42 GMT 2023
PRIMARY
DRUG BANK
DB14778
Created by admin on Sat Dec 16 17:27:42 GMT 2023 , Edited by admin on Sat Dec 16 17:27:42 GMT 2023
PRIMARY
FDA UNII
FPW3780T3E
Created by admin on Sat Dec 16 17:27:42 GMT 2023 , Edited by admin on Sat Dec 16 17:27:42 GMT 2023
PRIMARY
From To
1_22 1_96
1_144 1_200
1_257 1_317
1_363 1_421
2_22 2_96
2_144 2_200
2_257 2_317
2_363 2_421
1_131 3_216
1_219 2_219
1_220 2_220
1_223 2_223
1_226 2_226
2_131 4_216
3_22 3_90
3_139 3_198
4_22 4_90
4_139 4_198
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_293
N 2_293
Related Record Type Details
TARGET -> INHIBITOR
doi: 10.1172/JCI83731
IN-VIVO
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL