POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 1

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 11:56:29 UTC 2023` Edited by `admin` on `Sat Dec 16 11:56:29 UTC 2023`
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	FP8E4M5I14
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 1

Common Name

English

VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT KV4

Common Name

English

VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT KV3.1

Common Name

English

NGK2

Common Name

English

Code System Code Type Description

FDA UNII

FP8E4M5I14

Created by admin on Sat Dec 16 11:56:29 UTC 2023 , Edited by admin on Sat Dec 16 11:56:29 UTC 2023

PRIMARY

UNIPROT

P48547

Created by admin on Sat Dec 16 11:56:29 UTC 2023 , Edited by admin on Sat Dec 16 11:56:29 UTC 2023

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_220
N	1_229

Related Record Type Details


					BH3B64OKL9

DALFAMPRIDINE

AGONIST -> TARGET


					46P8AHZ243

AUT-00206

POSITIVE ALLOSTERIC MODULATOR (PAM)->TARGET

Comments:

AUT00206 positively modulates recombinant human Kv3.1 and Kv3.2 mediated currents, associated with a leftward shift of channel activation. The compound has a weaker effect on Kv3.3 and Kv3.4 channels, and little or no effect on other ion channels tested.

Amount:


					QZ8ETV7QYU

AUT-00201

MODULATOR->TARGET

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL
Molecular Formula	CHEMICAL