NITROSULFATHIAZOLE

First approved in 1949

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H7N3O4S2
Molecular Weight	285.3
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[O-][N+](=O)C1=CC=C(C=C1)S(=O)(=O)NC2=NC=CS2

InChI

InChIKey=CIASIHHEOGXVOM-UHFFFAOYSA-N

InChI=1S/C9H7N3O4S2/c13-12(14)7-1-3-8(4-2-7)18(15,16)11-9-10-5-6-17-9/h1-6H,(H,10,11)

HIDE SMILES / InChI

Molecular Formula	C9H7N3O4S2
Molecular Weight	285.3
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://books.google.ru/books?id=07g30rxCA0EC&pg=PA526&lpg=PA526&dq=NITROSULFATHIAZOLE retrieved from Medicinal Chemistry By Ashutosh Kar, p.526. | https://www.chemicalbook.com/ChemicalProductProperty_EN_CB91179339.htm | https://pubs.acs.org/doi/pdf/10.1021/ba-1964-0045.ch003?src=recsys | https://www.ncbi.nlm.nih.gov/pubmed/18857665 | https://www.ncbi.nlm.nih.gov/pubmed/15428235

Nitrosulfathiazole, a sulfonamide drug, is an antibacterial agent. It was marketed under the brand name Nisulfazole (Sterling Winthrop). Nisulfazole was used in the treatment of ulcerative colitis.

Approval Year

Sourcing

Vendor/Aggregator	ID	URL
AAA Chemistry	AR-1C8097
ABI Chem	AC1L1UJQ
ABI Chem	AC1Q6W1Z
Alinda	IBS-E0814983
Alinda	IBS-L0136628
Aronis	SYN2012/01297
Asinex	BAS 00315360
AsisChem	F90289
Aurora Fine Chemicals LLC	A18.866.423	http://online.aurorafinechemicals.com/info?ID=A18.866.423
BOC Sciences	473-42-7
ChemBridge	5243466
ChemDiv	Y031-7746
ChemTik	CTK4I9868
Chemhere	Achem119601
Chemhere	Pubchem29355
Chemieliva Pharmaceutical Co., Ltd	PBCM0588879
Chemspace	CSSS00015358772	https://chem-space.com/CSSS00015358772
Enamine	Z56115349
Innovapharm	VT-00356579
Lab Network	LN01087455
MolPort	MolPort-001-507-061
NovoSeek	10127
Otava	10000324
Princeton BioMolecular Research	OSSK_604821
Scientific Exchange	K-018826
THE BioTek	bt-372079	https://www.thebiotek.com/product/others/bt-372079
TimTec	ST50703760
Vitas-M Laboratory	STL260521
ZINC	ZINC000000198656	http://zinc15.docking.org/substances/ZINC000000198656
Zelinsky Institute	UZI/9050842
eMolecules	1190457
mcule	MCULE-9072425872	https://mcule.com/MCULE-9072425872/

PubMed

Title	Date	PubMed
The use of nisulfazole in the treatment of ulcerative colitis.	1949 Sep	18137531
NEW and nonofficial remedies: p-nitrosulfathiazole; nisulfazole.	1950 Jul 29	15428235
Comparison of the in vitro activity of nisulfazole with that of other sulfonamides.	1950 Jun	15422227
A method for the rectal use of nisulfazole in chronic ulcerative colitis.	1952 Mar	14908254

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:22:41 GMT 2023` Edited by `admin` on `Fri Dec 15 18:22:41 GMT 2023`
Record UNII	FO9CU4TX7J
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NITROSULFATHIAZOLE

Official Name

English

P-NITROSULFATHIAZOLE

Common Name

English

nitrosulfathiazole [INN]

Common Name

English

PARA-NITROSULFATHIAZOLE

Common Name

English

Code System Code Type Description

SMS_ID

100000084123