TETRACHLOROBISPHENOL A

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H12Cl4O2
Molecular Weight	366.067
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(C1=CC(Cl)=C(O)C(Cl)=C1)C2=CC(Cl)=C(O)C(Cl)=C2

InChI

InChIKey=KYPYTERUKNKOLP-UHFFFAOYSA-N

InChI=1S/C15H12Cl4O2/c1-15(2,7-3-9(16)13(20)10(17)4-7)8-5-11(18)14(21)12(19)6-8/h3-6,20-21H,1-2H3

HIDE SMILES / InChI

Molecular Formula	C15H12Cl4O2
Molecular Weight	366.067
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame retardants, their metabolites, and chemical mixtures in house dust.	2015-02	25314719
Halogenated bisphenol-A analogs act as obesogens in zebrafish larvae (Danio rerio).	2014-05	24591153
PBDE: structure-activity studies for the inhibition of hepatitis C virus NS3 helicase.	2014-04-02	24699145
In vitro study on the agonistic and antagonistic activities of bisphenol-S and other bisphenol-A congeners and derivatives via nuclear receptors.	2013-10-01	23714657
Mimicking of estradiol binding by flame retardants and their metabolites: a crystallographic analysis.	2013-10	23959441
Peroxisome proliferator-activated receptor γ is a target for halogenated analogs of bisphenol A.	2011-09	21561829
Characterization of novel ligands of ERα, Erβ, and PPARγ: the case of halogenated bisphenol A and their conjugated metabolites.	2011-08	21622942
Biodegradation of bisphenols with immobilized laccase or tyrosinase on polyacrylonitrile beads.	2011-06	21125313
Anti-thyroid hormone activity of bisphenol A, tetrabromobisphenol A and tetrachlorobisphenol A in an improved reporter gene assay.	2009-08	19457453
Determination of tetrabromobisphenol-A, tetrachlorobisphenol-A and bisphenol-A in soil by ultrasonic assisted extraction and gas chromatography-mass spectrometry.	2009-07-17	19524246
A standardized method for assessment of oxidative transformations of brominated phenols in water.	2008-01	17897700
A new bioluminescent cellular assay to measure the transcriptional effects of chemicals that modulate the alpha-1 thyroid hormone receptor.	2007-09	17532181
Bisphenol-A and chlorinated derivatives in adipose tissue of women.	2007-03-01	17689919
Effect of bisphenol A, tetrachlorobisphenol A and pentachlorophenol on the transcriptional activities of androgen receptor-mediated reporter gene.	2006-11	16893599
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006-11	16497524
Biosensor recognition of thyroid-disrupting chemicals using transport proteins.	2006-02-15	16478101
Simultaneous determination of tetrabromobisphenol A, tetrachlorobisphenol A, bisphenol A and other halogenated analogues in sediment and sludge by high performance liquid chromatography-electrospray tandem mass spectrometry.	2005-12-02	16298182
Inhibitory effects of environmental chemicals on protein disulfide isomerase in vitro.	2005-12	16617682
In vitro and in vivo analysis of the thyroid disrupting activities of phenolic and phenol compounds in Xenopus laevis.	2005-03	15590892
Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis.	2005-02-18	15680168
Effects of the environmental oestrogens bisphenol A, tetrachlorobisphenol A, tetrabromobisphenol A, 4-hydroxybiphenyl and 4,4'-dihydroxybiphenyl on oestrogen receptor binding, cell proliferation and regulation of oestrogen sensitive proteins in the human breast cancer cell line MCF-7.	2003-04	12753421
Thyroid hormonal activity of the flame retardants tetrabromobisphenol A and tetrachlorobisphenol A.	2002-04-26	12054637
Anaerobic biotransformation of tetrabromobisphenol A, tetrachlorobisphenol A, and bisphenol A in estuarine sediments.	2002-02-15	11878385
2,2',6,6'-Tetrachloro-4,4'-propane-2,2-diyldiphenol, 2,2',6-tribromo-4,4'-propane-2,2-diyldiphenol and 2,2',6,6'-tetrabromo-4,4'-propane-2,2-diyldiphenol.	2001-11	11706259
Potent competitive interactions of some brominated flame retardants and related compounds with human transthyretin in vitro.	2000-07	10869457

Substance Class	Chemical Created by `admin` on `Mon Mar 31 20:39:39 GMT 2025` Edited by `admin` on `Mon Mar 31 20:39:39 GMT 2025`
Record UNII	FO0P9ET4BN
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2,2',6,6'-TETRACHLOROBISPHENOL A

Preferred Name

English

TETRACHLOROBISPHENOL A

Systematic Name

English

4,4'- (1-METHYLETHYLIDENE)BIS(2,6-DICHLOROPHENOL)

Systematic Name

English

PHENOL, 4,4'-(1-METHYLETHYLIDENE)BIS(2,6-DICHLORO-

Systematic Name

English

2,2-BIS(4-HYDROXY-3,5-DICHLOROPHENYL)PROPANE

Systematic Name

English

3,3',5,5'-TETRACHLOROBISPHENOL A

Common Name

English

NSC-18248

Code

English

NSC-67465

Code

English

PHENOL, 4,4'-ISOPROPYLIDENEBIS(2,6-DICHLORO-

Systematic Name

English

2,2',6,6'-TETRACHLOROBISPHENOL A [HSDB]

Common Name

English

3,5,3',5'-TETRACHLOROBISPHENOL A

Common Name

English

2,2-BIS(3,5-DICHLORO-4-HYDROXYPHENYL)PROPANE

Systematic Name

English

Code System Code Type Description

NSC

18248