U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:10:09 GMT 2023
Edited
by admin
on Sat Dec 16 15:10:09 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
FME52R2SGN
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GEPTANOLIMAB
INN  
Official Name English
Geptanolimab [WHO-DD]
Common Name English
geptanolimab [INN]
Common Name English
HUMANIZED IGG4 ANTIBODY DIRECTED AGAINST THE NEGATIVE IMMUNOREGULATORY HUMAN CELL SURFACE RECEPTOR PROGRAMMED CELL DEATH 1 (PD-1/PDCD1/PD1) WITH LOW ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY AND COMPLEMENT-DEPENDENT CYTOTOXICITY
Common Name English
CBT-501
Code English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)), MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN (1-440) (VH (HOMO SAPIENSIGHV7-4-1*02 (85.7%)-(IGHD)-IGHJ4*01 (100%)) CDR-IMGT (8.8.7) (26-33.51-58.97-103) (1-114)-HOMO
Common Name English
GB226
Code English
GB-226
Code English
MMUNOGLOBULIN G4 (232-PROLINE,DE-451-LYSINE), ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) (HUMAN-MUS MUSCULUS MONOCLONAL GB226 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL GB226 .KAPPA.-CHAIN, DIMER
Common Name English
APL-501
Code English
GENOLIMZUMAB
INN  
Common Name English
Code System Code Type Description
NCI_THESAURUS
C148159
Created by admin on Sat Dec 16 15:10:10 GMT 2023 , Edited by admin on Sat Dec 16 15:10:10 GMT 2023
PRIMARY
CAS
2135810-45-4
Created by admin on Sat Dec 16 15:10:10 GMT 2023 , Edited by admin on Sat Dec 16 15:10:10 GMT 2023
NO STRUCTURE GIVEN
CAS
2348469-43-0
Created by admin on Sat Dec 16 15:10:10 GMT 2023 , Edited by admin on Sat Dec 16 15:10:10 GMT 2023
PRIMARY
FDA UNII
FME52R2SGN
Created by admin on Sat Dec 16 15:10:10 GMT 2023 , Edited by admin on Sat Dec 16 15:10:10 GMT 2023
PRIMARY
INN
11436
Created by admin on Sat Dec 16 15:10:10 GMT 2023 , Edited by admin on Sat Dec 16 15:10:10 GMT 2023
PRIMARY
From To
1_22 1_96
2_22 2_96
2_128 4_217
2_141 2_197
2_255 2_315
1_128 3_217
2_361 2_419
3_23 3_92
3_137 3_197
4_23 4_92
4_137 4_197
1_141 1_197
1_220 2_220
1_223 2_223
1_255 1_315
1_361 1_419
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_291
N 2_291
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL