TRIMETHYLAMINE OXIDE

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C3H9NO
Molecular Weight	75.1097
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[N+](C)(C)[O-]

InChI

InChIKey=UYPYRKYUKCHHIB-UHFFFAOYSA-N

InChI=1S/C3H9NO/c1-4(2,3)5/h1-3H3

HIDE SMILES / InChI

Molecular Formula	C3H9NO
Molecular Weight	75.1097
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
The reduced nicotinamide-adenine dinucleotide phosphate- and oxygen-dependent N-oxygenation of trimethylamine by Pseudomonas aminovorans.	1972 Jul	4404764
750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma.	1995 Mar 1	7762816
1H-NMR analysis of trimethylamine in urine for the diagnosis of fish-odour syndrome.	1997 Jul 25	9246418
Proton nuclear magnetic resonance spectral profiles of urine in type II diabetic patients.	1998 Jul	9665433
Effects of the osmolyte trimethylamine-N-oxide on conformation, self-association, and two-dimensional crystallization of myelin basic protein.	2002 Jul	12372316
1H and (13)C NMR spectroscopic analysis of human saliva.	2002 Jun	12097436
Protein synthesis inhibitors and the chemical chaperone TMAO reverse endoplasmic reticulum perturbation induced by overexpression of the iodide transporter pendrin.	2005 Apr 15	15784681
Diagnosis of suspected trimethylaminuria by NMR spectroscopy.	2005 Jan	15563884
Trimethylamine and trimethylamine oxide levels in normal women and women with bacterial vaginosis reflect a local metabolism in vaginal secretion as compared to urine.	2005 Jul-Aug	16086821
Rapid screening assay of trimethylaminuria in urine with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.	2007	17510942
Trimethylamine oxide suppresses stress-induced alteration of organic anion transport in choroid plexus.	2007 Feb	17234624
Natural disordered sequences in the amino terminal domain of nuclear receptors: lessons from the androgen and glucocorticoid receptors.	2007 Mar 9	17464357
Characterization of organic anion-transporting polypeptide (Oatp) 1a1 and 1a4 null mice reveals altered transport function and urinary metabolomic profiles.	2011 Aug	21561886

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:12:26 UTC 2023` Edited by `admin` on `Fri Dec 15 17:12:26 UTC 2023`
Record UNII	FLD0K1SJ1A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRIMETHYLAMINE OXIDE

Official Name

English

FEMA NO. 4245

Code

English

N,N-DIMETHYLMETHANAMINE N-OXIDE

Systematic Name

English

TMAO

Common Name

English

TRIMETHYLAMINE N-OXIDE [MI]

Common Name

English

TRIMETHYLAMINE OXIDE [FHFI]

Common Name

English

NSC-408426

Code

English

TRIMETHYLAMINE OXIDE [INCI]

Common Name

English

TRIMETHYLAMINE N-OXIDE

Systematic Name

English

Classification Tree Code System Code

JECFA EVALUATION

TRIMETHYLAMINE OXIDE