U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 17:21:14 UTC 2021
Edited
by admin
on Sat Jun 26 17:21:14 UTC 2021
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
FL08SGO9XA
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SIMLUKAFUSP ALFA
USAN   INN  
Official Name English
RO-6874281
Preferred Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN SEPRASE) (HUMAN MONOCLONAL FAP-IL-2V HEAVY CHAIN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC LINKER) FUSION PROTEIN WITH INTERLEUKIN 2 (HUMAN MUTANT QM IL-2), DISULFIDE WITH HUMAN MONOCLONAL FAP-IL-2V LIGHT CHAIN, DIMER WITH IM
Common Name English
RG-7461
Code English
RG7461
Code English
RO6874281
Code English
SIMLUKAFUSP ALFA [WHO-DD]
Common Name English
FAP-IL2V FP RO6874281
Code English
FAP-IL-2V
Code English
SIMLUKAFUSP ALFA [INN]
Common Name English
ANTI-FAP/INTERLEUKIN-2 FUSION PROTEIN RO6874281
Common Name English
FAP-IL2V
Code English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS PROLYL ENDOPEPTIDASE FAP (FIBROBLAST ACTIVATION PROTEIN ALPHASURFACE-EXPRESSED PROTEASESEPRASEEC=3.4.21.26)).OMEGA. MONO-LINKED TO MODIFIED (HOMO SAPIENS INTERLEUKIN-2 (T-CELL GROWTH FACTOR, IL-2, ALDESLEUKIN))
Common Name English
SIMLUKAFUSP ALFA [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C2139
Created by admin on Sat Jun 26 17:21:14 UTC 2021 , Edited by admin on Sat Jun 26 17:21:14 UTC 2021
Code System Code Type Description
INN
11116
Created by admin on Sat Jun 26 17:21:14 UTC 2021 , Edited by admin on Sat Jun 26 17:21:14 UTC 2021
PRIMARY
FDA UNII
FL08SGO9XA
Created by admin on Sat Jun 26 17:21:14 UTC 2021 , Edited by admin on Sat Jun 26 17:21:14 UTC 2021
PRIMARY
NCI_THESAURUS
C129383
Created by admin on Sat Jun 26 17:21:14 UTC 2021 , Edited by admin on Sat Jun 26 17:21:14 UTC 2021
PRIMARY
CAS
1776942-10-9
Created by admin on Sat Jun 26 17:21:14 UTC 2021 , Edited by admin on Sat Jun 26 17:21:14 UTC 2021
PRIMARY
From To
1_22 1_96
1_144 1_200
1_220 3_215
1_226 2_226
1_229 2_229
1_261 1_321
1_367 1_425
1_354 2_349
1_519 1_566
2_22 2_96
2_144 2_200
2_220 4_215
2_261 2_321
2_367 2_425
3_23 3_89
3_135 3_195
4_23 4_89
4_135 4_195
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
TARGET -> AGONIST
TARGET->ANTIGEN
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL