Adimanebart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 19:59:54 GMT 2025` Edited by `admin` on `Wed Apr 02 19:59:54 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|LAMDA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	FJK85PF3WY
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ARGX-119

Preferred Name

English

Adimanebart

Official Name

English

ARGX 119

Common Name

English

3B2g2m1-hlgG1 LALAdelk

Common Name

English

Immunoglobulin G1 [238-alanine,239-alanine,de-C-terminal-lysine], anti-(human receptor tyrosine kinase MuSK) (human-Lama glama monoclonal ARGX-119 ?1-chain), disulfide with human-Lama glama monoclonal ARGX-119 ?-chain, dime

Common Name

English

Immunoglobulin G, anti-(human muscle-specific tyrosine-protein kinase) (humanized monoclonal ARGX-119 heavy chain), disulfide with humanized monoclonal ARGX-119 light chain, dimer

Common Name

English

adimanebart [INN]

Common Name

English

Code System Code Type Description

CAS

2966023-63-0

Created by admin on Wed Apr 02 19:59:54 GMT 2025 , Edited by admin on Wed Apr 02 19:59:54 GMT 2025

NO STRUCTURE GIVEN

FDA UNII

FJK85PF3WY

Created by admin on Wed Apr 02 19:59:54 GMT 2025 , Edited by admin on Wed Apr 02 19:59:54 GMT 2025

PRIMARY

CAS

3011838-77-7

Created by admin on Wed Apr 02 19:59:54 GMT 2025 , Edited by admin on Wed Apr 02 19:59:54 GMT 2025

PRIMARY

INN

13433

Created by admin on Wed Apr 02 19:59:54 GMT 2025 , Edited by admin on Wed Apr 02 19:59:54 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_148	2_204
2_224	4_217
2_265	2_325
1_148	1_204
2_371	2_429
3_22	3_90
3_140	3_199
4_22	4_90
4_140	4_199
1_224	3_217
1_230	2_230
1_233	2_233
1_265	1_325
1_371	1_429

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_301
N	2_301

Related Record Type Details


					HWR3M9EC3V

MUSCLE, SKELETAL RECEPTOR TYROSINE-PROTEIN KINASE

TARGET->LIGAND

Related Record Type Details


					FJK85PF3WY

Adimanebart

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[3_1] [4_1]	N-TERMINUS	Q	Amount:	PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
LALA mutations	PROTEIN FEATURE
variable region	PROTEIN FEATURE
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL