PULOCIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 11:18:00 GMT 2025` Edited by `admin` on `Wed Apr 02 11:18:00 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	FDL8DA4XV4
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AK-109

Preferred Name

English

PULOCIMAB

Official Name

English

pulocimab [INN]

Common Name

English

AK109

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2) (HUMAN MONOCLONAL AK109 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL AK109 .KAPPA.-CHAIN, DIMER

Common Name

English

Pulocimab [WHO-DD]

Common Name

English

Code System Code Type Description

SMS_ID

300000039146

Created by admin on Wed Apr 02 11:18:00 GMT 2025 , Edited by admin on Wed Apr 02 11:18:00 GMT 2025

PRIMARY

INN

11807

Created by admin on Wed Apr 02 11:18:00 GMT 2025 , Edited by admin on Wed Apr 02 11:18:00 GMT 2025

PRIMARY

NCI_THESAURUS

C182005

Created by admin on Wed Apr 02 11:18:00 GMT 2025 , Edited by admin on Wed Apr 02 11:18:00 GMT 2025

PRIMARY

CAS

2428381-49-9

Created by admin on Wed Apr 02 11:18:00 GMT 2025 , Edited by admin on Wed Apr 02 11:18:00 GMT 2025

PRIMARY

FDA UNII

FDL8DA4XV4

Created by admin on Wed Apr 02 11:18:00 GMT 2025 , Edited by admin on Wed Apr 02 11:18:00 GMT 2025

PRIMARY

From	To
4_134	4_194
3_134	3_194
4_23	4_88
3_23	3_88
2_366	2_424
1_366	1_424
2_260	2_320
1_260	1_320
1_228	2_228
1_225	2_225
2_219	4_214
1_219	3_214
2_143	2_199
1_143	1_199
2_22	2_96
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_296
N	2_296

Related Record Type Details


					798536Z7S0

VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2

TARGET->LIGAND

Amount:

Related Record Type Details


					FDL8DA4XV4

PULOCIMAB

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL					LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL