Sontigidomide

Details

Stereochemistry	RACEMIC
Molecular Formula	C26H22F3N3O5
Molecular Weight	513.4652
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC(F)(F)C1(CC1)C2=CC=C(C=C2)C(=O)C(=O)NCC3=CC=C4C(=O)N(CC4=C3)C5CCC(=O)NC5=O

InChI

InChIKey=SKAIDPMCBUKTDS-UHFFFAOYSA-N

InChI=1S/C26H22F3N3O5/c27-26(28,29)25(9-10-25)17-4-2-15(3-5-17)21(34)23(36)30-12-14-1-6-18-16(11-14)13-32(24(18)37)19-7-8-20(33)31-22(19)35/h1-6,11,19H,7-10,12-13H2,(H,30,36)(H,31,33,35)

HIDE SMILES / InChI

Molecular Formula	C26H22F3N3O5
Molecular Weight	513.4652
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:49:45 GMT 2023` Edited by `admin` on `Sat Dec 16 18:49:45 GMT 2023`
Record UNII	FDD2NVW84X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Sontigidomide

Official Name

English

N-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-α-oxo-4-[1-(trifluoromethyl)cyclopropyl]benzeneacetamide

Systematic Name

English

Benzeneacetamide, N-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-α-oxo-4-[1-(trifluoromethyl)cyclopropyl]-

Systematic Name

English

sontigidomide [INN]

Common Name

English

Code System Code Type Description

FDA UNII

FDD2NVW84X

Created by admin on Sat Dec 16 18:49:45 GMT 2023 , Edited by admin on Sat Dec 16 18:49:45 GMT 2023

PRIMARY

INN

12637

Created by admin on Sat Dec 16 18:49:45 GMT 2023 , Edited by admin on Sat Dec 16 18:49:45 GMT 2023

PRIMARY

PUBCHEM

155316421

Created by admin on Sat Dec 16 18:49:45 GMT 2023 , Edited by admin on Sat Dec 16 18:49:45 GMT 2023

PRIMARY

CAS

2560577-69-5

Created by admin on Sat Dec 16 18:49:45 GMT 2023 , Edited by admin on Sat Dec 16 18:49:45 GMT 2023

PRIMARY

Related Record Type Details


					FDD2NVW84X

Sontigidomide

ACTIVE MOIETY

Comments:

BTX-1188 is a novel small molecule cereblon (CRBN) binder that promotes the degradation of a neosubstrate G1 to S phase transition 1 (GSPT1), a translation termination factor, as well as Ikaros

Amount: