Zocaglusagene Nuzaparvovec

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 09:16:05 GMT 2025` Edited by `admin` on `Wed Apr 02 09:16:05 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family	Parvoviridae
Organism Genus	Dependovirus
Organism Species	adeno-associated virus
Author	NONE
Infraspecific Type	RECOMBINANT VECTOR
Infraspecific Name	rAAV8-eMCK-hGAA
Part	whole
Record UNII	FDB4GQ8A3Y
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AT-845

Preferred Name

English

Zocaglusagene Nuzaparvovec

Official Name

English

AT845

Common Name

English

DNA (recombinant adeno-associated virus vector AT845 mouse muscle-type creatine kinase enhancer plus mouse muscle-type creatine kinase promoter plus human lysosomal ?-glucosidase precursor codon-optimized transgene plus simian virus 40 polyadenylation si

Common Name

English

zocaglusagene nuzaparvovec [INN]

Common Name

English

Recombinant, non-replicating adeno-associated virus serotype 8 (rAAV8) vector encoding codon-optimized human acid alpha-glucosidase (GAA), also called lysosomal ?-glucosidase or acid maltase, under control of a mouse muscle creatine kinase (MCK) enhancer

Common Name

English

ZOCAGLUSAGENE NUZAPARVOVEC [USAN]

Common Name

English

Code System Code Type Description

FDA UNII

FDB4GQ8A3Y