Approval Year
Substance Class |
Nucleic Acid
Created
by
admin
on
Edited
Sat Dec 16 19:30:41 GMT 2023
by
admin
on
Sat Dec 16 19:30:41 GMT 2023
|
Nucleic Acid Type | dsRNA |
Nucleic Acid Subtype | |
Sequence Type | COMPLETE |
Record UNII |
FBX7PTD863
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English |
Code System | Code | Type | Description | ||
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12370
Created by
admin on Sat Dec 16 19:30:41 GMT 2023 , Edited by admin on Sat Dec 16 19:30:41 GMT 2023
|
PRIMARY | |||
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C190443
Created by
admin on Sat Dec 16 19:30:41 GMT 2023 , Edited by admin on Sat Dec 16 19:30:41 GMT 2023
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PRIMARY | |||
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2646703-64-0
Created by
admin on Sat Dec 16 19:30:41 GMT 2023 , Edited by admin on Sat Dec 16 19:30:41 GMT 2023
|
PRIMARY | |||
|
FBX7PTD863
Created by
admin on Sat Dec 16 19:30:41 GMT 2023 , Edited by admin on Sat Dec 16 19:30:41 GMT 2023
|
PRIMARY |
Sugar | Site Range | Site Count |
---|---|---|
2'-Fluoro-Ribose | 1_7-1_9;2_2;2_4;2_6;2_8;2_10;2_12;2_14;2_16;2_18 | 12 / 38 |
2'-O-Methyl-Ribose | 1_1-1_6;1_10-1_19;2_1;2_3;2_5;2_7;2_9;2_11;2_13;2_15;2_17;2_19 | 26 / 38 |
Linkage | Site Range | Site Count |
---|---|---|
Phosphate | 1_3-1_17;2_4-2_17 | 29 / 36 |
Phosporothioate | 1_2;1_18-1_19;2_2-2_3;2_18-2_19 | 7 / 36 |
Related Record | Type | Details | ||
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TARGET->INHIBITOR OF EXPRESSION |
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Related Record | Type | Details | ||
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ACTIVE MOIETY |
apolipoprotein(a) synthesis reducer
|
Structural Modifications
Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
---|---|---|---|---|---|---|
NUCLEOTIDE SUBSTITUTION | [1_1] | 5'-TERMINUS | Zerlasiran 5'-modification | VTF9MMJ8CN |