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Details

Stereochemistry ACHIRAL
Molecular Formula C2H7N5
Molecular Weight 101.1105
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BIGUANIDE

SMILES

NC(=N)NC(N)=N

InChI

InChIKey=XNCOSPRUTUOJCJ-UHFFFAOYSA-N
InChI=1S/C2H7N5/c3-1(4)7-2(5)6/h(H7,3,4,5,6,7)

HIDE SMILES / InChI

Molecular Formula C2H7N5
Molecular Weight 101.1105
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Biguanide has been investigated for the treatment of Diabetes Mellitus. The term "biguanidine" often refers specifically to a class of drugs that have a broad range of medical indications. Besides recent experiments have shown that biguanide could be a modifiable pharmacophore for the synthesis of therapeutic cysteinyl cathepsins inhibitors with a wide range of potencies and specificities. It is known that excessive activities of cysteinyl cathepsins contribute to the progress of many diseases.

Approval Year

PubMed

Patents

Substance Class Chemical
Record UNII
FB4Q52I9K2
Record Status Validated (UNII)
Record Version