Drotokibart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 19:56:02 GMT 2025` Edited by `admin` on `Wed Apr 02 19:56:02 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4\|KAPPA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	FA6H9P65L6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

H-gamma4 heavy chain humanized (1-445) [VH (Homo sapiens IGHV3-48*01 (88.8%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228),

Preferred Name

English

Drotokibart

Common Name

English

immunoglobulin G4-kappa, anti-[Homo sapiens IL4R (interleukin 4 receptor, IL4RA, IL-4RA, interleukin 13 receptor, CD124)], humanized monoclonal antibody

Common Name

English

Immunoglobulin G4 [226-proline], anti-(human interleukin-4 receptor subunit ?) (human-Mus musculus monoclonal ER006-01 ?4-chain), disulfide with human-Mus musculus monoclonal ER006-01 ?-chain, dimer

Common Name

English

drotokibart [INN]

Common Name

English

Code System Code Type Description

CAS

2925270-26-2