TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 03:11:11 GMT 2025` Edited by `admin` on `Wed Apr 02 03:11:11 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	F9FD19UQZ9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

5'-PHOSPHORIBOSYLGLYCINAMIDE TRANSFORMYLASE

Preferred Name

English

TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3

Common Name

English

GARS

Common Name

English

PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE

Common Name

English

PRGS

Common Name

English

PHOSPHORIBOSYL-AMINOIMIDAZOLE SYNTHETASE

Common Name

English

PGFT

Common Name

English

PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE

Common Name

English

PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE

Common Name

English

AIR SYNTHASE

Common Name

English

GART

Common Name

English

AIRS

Common Name

English

PHOSPHORIBOSYLAMINE--GLYCINE LIGASE

Common Name

English

GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE

Common Name

English

GAR TRANSFORMYLASE

Common Name

English

GARFT

Common Name

English

Code System Code Type Description

FDA UNII

F9FD19UQZ9

Created by admin on Wed Apr 02 03:11:11 GMT 2025 , Edited by admin on Wed Apr 02 03:11:11 GMT 2025

PRIMARY

UNIPROT

P22102

Created by admin on Wed Apr 02 03:11:11 GMT 2025 , Edited by admin on Wed Apr 02 03:11:11 GMT 2025

PRIMARY

Related Record Type Details


					IC32U30905

AG-2034

INHIBITOR -> TARGET


					5C78S9M5SG

AG-150

INHIBITOR -> TARGET

Amount:


					XA350X0B4R

LY-309887

INHIBITOR -> TARGET

Qualification:

Ki

Amount:


					04Q9AIZ7NO

PEMETREXED

INHIBITOR -> TARGET

Structural Modifications

Modification Type	Location Site	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_1]	N-ACETYLALANINE	26C4VY6Z0M
AMINO ACID SUBSTITUTION	[1_349]	N6-ACETYLLYSINE	470AD5VY1X
AMINO ACID SUBSTITUTION	[1_439]	DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL