NITROPARACETAMOL

CC(=O)NC1=CC=C(OC(=O)CCCO[N+]([O-])=O)C=C1

InChIKey=XTMOQAKCOFLCRZ-UHFFFAOYSA-N

InChI=1S/C12H14N2O6/c1-9(15)13-10-4-6-11(7-5-10)20-12(16)3-2-8-19-14(17)18/h4-7H,2-3,8H2,1H3,(H,13,15)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Nitroparacetamol exhibits anti-inflammatory and anti-nociceptive activity.	2000 Aug	10928944
NCX-701 (nitroparacetamol) is an effective antinociceptive agent in rat withdrawal reflexes and wind-up.	2002 Mar	11906970
Cardioprotective effects of nitroparacetamol and paracetamol in acute phase of myocardial infarction in experimental rats.	2006 Feb	16172162
Enhancement of the analgesic activity of paracetamol and nitroparacetamol by the oral administration of all-trans retinoic acid.	2006 Sep	16870215

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:40:40 GMT 2023` Edited by `admin` on `Fri Dec 15 15:40:40 GMT 2023`
Record UNII	F8Y1ZV5V9P
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

NITROPARACETAMOL

Common Name

English

NCX-701

Code

English

BUTANOIC ACID, 4-(NITROOXY)-, 4-(ACETYLAMINO)PHENYL ESTER

Systematic Name

English

4-(NITROOXY)BUTANOIC ACID 4-ACETYLAMINOPHENYL ESTER

Systematic Name

English

Code System Code Type Description

DRUG BANK

DB05409