STREPTIDINE DIHYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H18N6O4.2ClH
Molecular Weight	335.188
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of STREPTIDINE DIHYDROCHLORIDE

Structure Search

SMILES

Cl.Cl.NC(=N)N[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@@H]1O

InChI

InChIKey=MVWOOTAUQKDAHW-LSTGYKGTSA-N

InChI=1S/C8H18N6O4.2ClH/c9-7(10)13-1-3(15)2(14-8(11)12)5(17)6(18)4(1)16;;/h1-6,15-18H,(H4,9,10,13)(H4,11,12,14);2*1H/t1-,2+,3-,4+,5-,6-;;

HIDE SMILES / InChI

Molecular Formula	C8H18N6O4
Molecular Weight	262.2663
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Vestibular histofluorescence could be due to accumulation of both the antibiotic and its derivative, streptidine, after acute streptomycin treatment in the guinea pig.	2001 Oct	11642734
kasT gene of Streptomyces kasugaensis M338-M1 encodes a DNA-binding protein which binds to intergenic region of kasU-kasJ in the kasugamycin biosynthesis gene cluster.	2002 Dec	12617515
Streptidine, a metabolic derivative produced after administration of streptomycin in vivo, is vestibulotoxic in rats.	2005 Apr	15736038
A direct HPLC method to estimate streptomycin and its putative ototoxic derivative, streptidine, in blood serum: application to streptomycin-treated humans.	2007 Jan 17	16956741
Rescue of the streptomycin antibiotic activity by using streptidine as a "decoy acceptor" for the aminoglycoside-inactivating enzyme adenyl transferase.	2007 Jul 19	17609790
Streptomycin action to the mammalian inner ear vestibular organs: comparison between pigmented guinea pigs and rats.	2007 Jul-Aug	17011831
LC-MS of streptomycin following desalting of a nonvolatile mobile phase and pH gradient.	2009 Oct	19764048

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:07:21 GMT 2023` Edited by `admin` on `Sat Dec 16 10:07:21 GMT 2023`
Record UNII	F7PR5YA64P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

STREPTIDINE DIHYDROCHLORIDE

Common Name

English

STREPTAMINE, N,N'-BIS(AMINOIMINOMETHYL)-, DIHYDROCHLORIDE

Common Name

English

STREPTIDINE DIHYDROCHLORIDE [MI]

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID10977193

Created by admin on Sat Dec 16 10:07:21 GMT 2023 , Edited by admin on Sat Dec 16 10:07:21 GMT 2023

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MERCK INDEX

m10222

Created by admin on Sat Dec 16 10:07:21 GMT 2023 , Edited by admin on Sat Dec 16 10:07:21 GMT 2023

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Merck Index

CAS

6160-28-7

Created by admin on Sat Dec 16 10:07:21 GMT 2023 , Edited by admin on Sat Dec 16 10:07:21 GMT 2023

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FDA UNII

F7PR5YA64P

Created by admin on Sat Dec 16 10:07:21 GMT 2023 , Edited by admin on Sat Dec 16 10:07:21 GMT 2023

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