STREPTIDINE DIHYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H18N6O4.2ClH
Molecular Weight	335.188
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of STREPTIDINE DIHYDROCHLORIDE

Structure Search

SMILES

Cl.Cl.NC(=N)N[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@@H]1O

InChI

InChIKey=MVWOOTAUQKDAHW-LSTGYKGTSA-N

InChI=1S/C8H18N6O4.2ClH/c9-7(10)13-1-3(15)2(14-8(11)12)5(17)6(18)4(1)16;;/h1-6,15-18H,(H4,9,10,13)(H4,11,12,14);2*1H/t1-,2+,3-,4+,5-,6-;;

HIDE SMILES / InChI

Molecular Formula	C8H18N6O4
Molecular Weight	262.2663
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
LC-MS of streptomycin following desalting of a nonvolatile mobile phase and pH gradient.	2009-10	19764048
Rescue of the streptomycin antibiotic activity by using streptidine as a "decoy acceptor" for the aminoglycoside-inactivating enzyme adenyl transferase.	2007-07-19	17609790
A direct HPLC method to estimate streptomycin and its putative ototoxic derivative, streptidine, in blood serum: application to streptomycin-treated humans.	2007-01-17	16956741
Streptomycin action to the mammalian inner ear vestibular organs: comparison between pigmented guinea pigs and rats.	2006-04-28	17011831
Molecular recognition of aminoglycoside antibiotics by bacterial defence proteins: NMR study of the structural and conformational features of streptomycin inactivation by Bacillus subtilis aminoglycoside-6-adenyl transferase.	2005-08-19	15984036
Streptidine, a metabolic derivative produced after administration of streptomycin in vivo, is vestibulotoxic in rats.	2005-04	15736038
A new family of glucose-1-phosphate/glucosamine-1-phosphate nucleotidylyltransferase in the biosynthetic pathways for antibiotics.	2005-02-16	15701005
kasT gene of Streptomyces kasugaensis M338-M1 encodes a DNA-binding protein which binds to intergenic region of kasU-kasJ in the kasugamycin biosynthesis gene cluster.	2002-12	12617515
Vestibular histofluorescence could be due to accumulation of both the antibiotic and its derivative, streptidine, after acute streptomycin treatment in the guinea pig.	2001-10	11642734

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:03:24 GMT 2025` Edited by `admin` on `Mon Mar 31 23:03:24 GMT 2025`
Record UNII	F7PR5YA64P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

STREPTIDINE DIHYDROCHLORIDE

Common Name

English

STREPTAMINE, N,N'-BIS(AMINOIMINOMETHYL)-, DIHYDROCHLORIDE

Preferred Name

English

STREPTIDINE DIHYDROCHLORIDE [MI]

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID10977193

Created by admin on Mon Mar 31 23:03:24 GMT 2025 , Edited by admin on Mon Mar 31 23:03:24 GMT 2025

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MERCK INDEX

m10222

Created by admin on Mon Mar 31 23:03:24 GMT 2025 , Edited by admin on Mon Mar 31 23:03:24 GMT 2025

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Merck Index

CAS

6160-28-7

Created by admin on Mon Mar 31 23:03:24 GMT 2025 , Edited by admin on Mon Mar 31 23:03:24 GMT 2025

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FDA UNII

F7PR5YA64P

Created by admin on Mon Mar 31 23:03:24 GMT 2025 , Edited by admin on Mon Mar 31 23:03:24 GMT 2025

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