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Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:09:38 UTC 2023
Edited
by admin
on Sat Dec 16 15:09:38 UTC 2023
Protein Type CYTOKINE
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
F74EZG47QK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RANKL (MEMBRANE BOUND)
Common Name English
TNF-RELATED ACTIVATION-INDUCED CYTOKINE (MEMBRANE BOUND)
Common Name English
RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA-B LIGAND (MEMBRANE BOUND)
Common Name English
TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 11 (MEMBRANE BOUND)
Common Name English
Code System Code Type Description
FDA UNII
F74EZG47QK
Created by admin on Sat Dec 16 15:09:38 UTC 2023 , Edited by admin on Sat Dec 16 15:09:38 UTC 2023
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_171
N 1_198
Related Record Type Details
INHIBITOR -> TARGET
Denosumab is a fully human monoclonal antibody that binds to RANKL, preventing it from binding its receptor RANK, and thereby inhibiting formation, action, and survival of osteoclasts
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL