VESLETEPLIRSEN

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 14:18:35 GMT 2023` Edited by `admin` on `Sat Dec 16 14:18:35 GMT 2023`
Nucleic Acid Type	OLIGONUCLEOTIDE
Nucleic Acid Subtype
Sequence Type	COMPLETE
Record UNII	F6U7EZ3N1Q
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

VESLETEPLIRSEN

Official Name

English

vesleteplirsen [INN]

Common Name

English

RNA, (P-DEOXY-P-(DIMETHYLAMINO))(2',3'-DIDEOXY-2',3'-IMINO-2',3'-SECO)(2'A->5')(C-M5U-C-C-A-A-C-A-M5U-C-A-A-G-G-A-A-G-A-M5U-G-G-C-A-M5U-M5U-M5U-C-M5U-A-(2'A-(N2-ACETYL-L-ARGINYL-L-ARGINYL-L-ARGINYL-L-ARGINYL-L-ARGINYL-L-ARGINYLGLYCYL))G), 5'-(P-(4-((2-(2

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C184817

Created by admin on Sat Dec 16 14:18:35 GMT 2023 , Edited by admin on Sat Dec 16 14:18:35 GMT 2023

PRIMARY

INN

11654

Created by admin on Sat Dec 16 14:18:35 GMT 2023 , Edited by admin on Sat Dec 16 14:18:35 GMT 2023

PRIMARY

CAS

2101570-09-4

Created by admin on Sat Dec 16 14:18:35 GMT 2023 , Edited by admin on Sat Dec 16 14:18:35 GMT 2023

PRIMARY

FDA UNII

F6U7EZ3N1Q

Created by admin on Sat Dec 16 14:18:35 GMT 2023 , Edited by admin on Sat Dec 16 14:18:35 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
morpholino	1_1-1_30	30 / 30

Linkage	Site Range	Site Count
Phosphoryldimethylamine	1_2-1_30	29 / 29

Related Record Type Details


					F6U7EZ3N1Q

VESLETEPLIRSEN

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOTIDE SUBSTITUTION	[1_30]	SITE_SPECIFIC			UNSPECIFIED SUBSTANCE	cd155a43 (not in database)
NUCLEOTIDE SUBSTITUTION	[1_1]	SITE_SPECIFIC			CASIMERSEN 5'-CYTOSINE MODIFICATION	8CQO07490I