TETRAMETHYLENEDISULFOTETRAMINE

O=S1(=O)N2CN3CN1CN(C2)S3(=O)=O

InChIKey=AGGKEGLBGGJEBZ-UHFFFAOYSA-N

InChI=1S/C4H8N4O4S2/c9-13(10)5-1-6-3-8(13)4-7(2-5)14(6,11)12/h1-4H2

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Combined diazepam and MK-801 therapy provides synergistic protection from tetramethylenedisulfotetramine-induced tonic-clonic seizures and lethality in mice.	2015-05	25783504
Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication.	2014-12-01	25448683
Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation.	2012-12	22889812
Differential antagonism of tetramethylenedisulfotetramine-induced seizures by agents acting at NMDA and GABA(A) receptors.	2012-11-15	23022509

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:52:58 GMT 2025` Edited by `admin` on `Mon Mar 31 22:52:58 GMT 2025`
Record UNII	F6TS3WME05
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

NSC-172824

Preferred Name

English

TETRAMETHYLENEDISULFOTETRAMINE

Common Name

English

TETRAMETHYLENEDISULFOTETRAMINE [MI]

Common Name

English

2,6-DITHIA-1,3,5,7-TETRAAZATRICYCLO(3.3.1.13,7)DECANE, 2,2,6,6-TETRAOXIDE

Systematic Name

English

TETS

Common Name

English

TETRAMETHYLENEDISULPHOTETRAMINE

Common Name

English

Code System Code Type Description

FDA UNII

F6TS3WME05