DESACETYL ACETAZOLAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H4N4O2S2
Molecular Weight	180.209
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=NN=C(S1)S(N)(=O)=O

InChI

InChIKey=VGMVBPQOACUDRU-UHFFFAOYSA-N

InChI=1S/C2H4N4O2S2/c3-1-5-6-2(9-1)10(4,7)8/h(H2,3,5)(H2,4,7,8)

HIDE SMILES / InChI

Molecular Formula	C2H4N4O2S2
Molecular Weight	180.209
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Acetazolamide-based fungal chitinase inhibitors.	2010-12-01	21044846
Synthesis, characterization and antiglaucoma activity of some novel pyrazole derivatives of 5-amino-1,3,4-thiadiazole-2-sulfonamide.	2010-11	20724038
Simultaneous determination of epinephrine, uric acid and xanthine in the presence of ascorbic acid using an ultrathin polymer film of 5-amino-1,3,4-thiadiazole-2-thiol modified electrode.	2009-08-04	19576392
Effects of new 5-amino-1,3,4-thiadiazole-2-sulfonamide derivatives on human carbonic anhydrase isozymes.	2009-05-01	19362844
Carbonic anhydrase inhibitors. Biphenylsulfonamides with inhibitory action towards the transmembrane, tumor-associated isozymes IX possess cytotoxic activity against human colon, lung and breast cancer cell lines.	2009-04	18608752
Amide derivatives with pyrazole carboxylic acids of 5-amino-1,3,4-thiadiazole 2-sulfonamide as new carbonic anhydrase inhibitors: synthesis and investigation of inhibitory effects.	2008-12	18618324
Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1,3,4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide to human isoform II.	2006-12-15	17000110
Carbonic anhydrase inhibitors. Inhibition of red blood cell ostrich (Struthio camelus) carbonic anhydrase with a series of aromatic and heterocyclic sulfonamides.	2005-08	16206834
Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.	2005-01-17	15603956
Carbonic anhydrase inhibitors: Schiff's bases of aromatic and heterocyclic sulfonamides and their metal complexes.	2004-06	15499998
Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives.	2003-05-22	12747790
Bile acid derivatives of 5-amino-1,3,4-thiadiazole-2-sulfonamide as new carbonic anhydrase inhibitors: synthesis and investigation of inhibition effects.	2002-08	12057645

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:48:57 GMT 2025` Edited by `admin` on `Mon Mar 31 18:48:57 GMT 2025`
Record UNII	F687N81LIZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

5-AMINO-1,3,4-THIADIAZOL-2-SULFONAMIDE

Preferred Name

English

DESACETYL ACETAZOLAMIDE

Common Name

English

NSC-22979

Code

English

ACETAZOLAMIDE RELATED COMPOUND D [USP-RS]

Common Name

English

2-AMINO-1,3,4-THIADAZOLE-5-SULFONAMIDE

Common Name

English

5-AMINO-1,3,4-THIADIAZOLE-2-SULFONAMIDE

Systematic Name

English

ACETAZOLAMIDE IMPURITY D [EP IMPURITY]

Common Name

English

TIO-URASIN

Common Name

English

2-AMINO-1,3,4-THIADIAZOLE-5-SULFONAMIDE

Systematic Name

English

DESACETYL ACETAZOLAMIDE [USP IMPURITY]

Common Name

English

CL-5343

Code

English

1,3,4-THIADIAZOLE-2-SULFONAMIDE, 5-AMINO-

Systematic Name

English

AMINO-1,3,4-THIADIAZOLE-5-SULFONAMIDE, 2-

Systematic Name

English

Code System Code Type Description

FDA UNII

F687N81LIZ