U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Thu Jul 06 18:22:39 UTC 2023
Edited
by admin
on Thu Jul 06 18:22:39 UTC 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
F660L4205N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA
Common Name English
SODIUM CHANNEL PROTEIN TYPE V SUBUNIT ALPHA
Common Name English
VOLTAGE-GATED SODIUM CHANNEL SUBUNIT ALPHA NAV1.5
Common Name English
SCN5A
Common Name English
SODIUM CHANNEL PROTEIN CARDIAC MUSCLE SUBUNIT ALPHA
Common Name English
Code System Code Type Description
PHAROS
Q14524
Created by admin on Thu Jul 06 18:22:39 UTC 2023 , Edited by admin on Thu Jul 06 18:22:39 UTC 2023
PRIMARY
FDA UNII
F660L4205N
Created by admin on Thu Jul 06 18:22:39 UTC 2023 , Edited by admin on Thu Jul 06 18:22:39 UTC 2023
PRIMARY
UNIPROT
Q14524
Created by admin on Thu Jul 06 18:22:39 UTC 2023 , Edited by admin on Thu Jul 06 18:22:39 UTC 2023
PRIMARY
WIKIPEDIA
NAV1.5
Created by admin on Thu Jul 06 18:22:39 UTC 2023 , Edited by admin on Thu Jul 06 18:22:39 UTC 2023
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_214
N 1_283
N 1_288
N 1_291
N 1_318
N 1_328
N 1_740
N 1_803
N 1_864
N 1_1365
N 1_1374
N 1_1380
N 1_1388
N 1_1736
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR RESISTANT -> TARGET
NaV1.5, NaV1.8, and NaV1.9 are tetrodotoxin-resistant to varying degrees
NON-INHIBITOR->OFF TARGET
failed to inhibit L-type calcium channel, or Nav1.5 sodium current at clinically relevant concentrations.
INHIBITOR -> TARGET
Kd
INHIBITOR -> TARGET
NON-INHIBITOR->OFF TARGET
IC50
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
Molecular Formula CHEMICAL