U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 12:47:42 GMT 2023
Edited
by admin
on Sat Dec 16 12:47:42 GMT 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
F660L4205N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA
Common Name English
SODIUM CHANNEL PROTEIN TYPE V SUBUNIT ALPHA
Common Name English
NAV1.5
Common Name English
VOLTAGE-GATED SODIUM CHANNEL SUBUNIT ALPHA NAV1.5
Common Name English
SCN5A
Common Name English
SODIUM CHANNEL PROTEIN CARDIAC MUSCLE SUBUNIT ALPHA
Common Name English
NAV-1.5
Common Name English
Code System Code Type Description
PHAROS
Q14524
Created by admin on Sat Dec 16 12:47:42 GMT 2023 , Edited by admin on Sat Dec 16 12:47:42 GMT 2023
PRIMARY
FDA UNII
F660L4205N
Created by admin on Sat Dec 16 12:47:42 GMT 2023 , Edited by admin on Sat Dec 16 12:47:42 GMT 2023
PRIMARY
UNIPROT
Q14524
Created by admin on Sat Dec 16 12:47:42 GMT 2023 , Edited by admin on Sat Dec 16 12:47:42 GMT 2023
PRIMARY
WIKIPEDIA
NAV1.5
Created by admin on Sat Dec 16 12:47:42 GMT 2023 , Edited by admin on Sat Dec 16 12:47:42 GMT 2023
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_214
N 1_283
N 1_288
N 1_291
N 1_318
N 1_328
N 1_740
N 1_803
N 1_864
N 1_1365
N 1_1374
N 1_1380
N 1_1388
N 1_1736
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR RESISTANT -> TARGET
NaV1.5, NaV1.8, and NaV1.9 are tetrodotoxin-resistant to varying degrees
NON-INHIBITOR->OFF TARGET
failed to inhibit L-type calcium channel, or Nav1.5 sodium current at clinically relevant concentrations.
INHIBITOR -> TARGET
Kd
INHIBITOR -> TARGET
NON-INHIBITOR->OFF TARGET
IC50
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
Molecular Formula CHEMICAL