ACETYLMETHIONINE SODIUM

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C7H12NO3S.Na
Molecular Weight	213.23
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].CSCC[C@H](NC(C)=O)C([O-])=O

InChI

InChIKey=COVZVRLKHWCGMW-RGMNGODLSA-M

InChI=1S/C7H13NO3S.Na/c1-5(9)8-6(7(10)11)3-4-12-2;/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11);/q;+1/p-1/t6-;/m0./s1

HIDE SMILES / InChI

Molecular Formula	C7H12NO3S
Molecular Weight	190.24
Charge	-1
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	Na
Molecular Weight	22.98976928
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Specific reaction of Met 35 in amyloid beta peptide with hypochlorous acid.	2010-07	20370566
Formation and hydrolysis of amide bonds by lipase A from Candida antarctica; exceptional features.	2010-02-21	20135048
A bulky platinum triamine complex that reacts faster with guanosine 5'-monophosphate than with N-acetylmethionine.	2010-02	19906431
X-ray spectroscopic approaches to the investigation and characterization of photochemical processes.	2009-07	19535861
Synthesis, cellular uptake and structure-activity relationships for potent cytotoxic trichloridoiridium(III) polypyridyl complexes.	2008-08	18472166
Characterization of a bifunctional aminoacylase/carboxypeptidase from radioresistant bacterium Deinococcus radiodurans R1.	2007-02-01	17129628
The role of N-acetyl-methioninate as a new stabilizer for albumin products.	2007-02-01	17045433
Density functional theory methods as powerful tools to elucidate amino acid oxidation mechanisms. A case study on methionine model peptide.	2007-01-18	17214501
In vivo metabolism of L-methionine in mice: evidence for stereoselective formation of methionine-d-sulfoxide and quantitation of other major metabolites.	2006-12	16963488
Probing the catalytic center of porcine aminoacylase 1 by site-directed mutagenesis, homology modeling and substrate docking.	2006-03	16567407
Interaction of N-acetylmethionine with a non-C2-symmetrical platinum diamine complex.	2005-11	16129491
Purification and characterization of a novel aminoacylase from Streptomyces mobaraensis.	2005-10	16244442
Effects of geometric isomerism in dinuclear antitumor platinum complexes on their interactions with N-acetyl-L-methionine.	2005-08	16091934
Pyridine-carboxylate complexes of platinum. Effect of N,O-chelate formation on model bifunctional DNA-DNA and DNA-protein interactions.	2005-07-25	16022522
Methionine radical cation: structural studies as a function of pH using X- and Q-band time-resolved electron paramagnetic resonance spectroscopy.	2005-07-07	16833920
Potential roles of flavin-containing monooxygenases in sulfoxidation reactions of l-methionine, N-acetyl-l-methionine and peptides containing l-methionine.	2005-01-17	15680226
Molecular cloning and biochemical characterization of L-N-carbamoylase from Sinorhizobium meliloti CECT4114.	2005	16254442
Structural basis for catalytic racemization and substrate specificity of an N-acylamino acid racemase homologue from Deinococcus radiodurans.	2004-09-03	15313614
Evolution of enzymatic activity in the enolase superfamily: structural studies of the promiscuous o-succinylbenzoate synthase from Amycolatopsis.	2004-05-18	15134446
Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress.	2004-04-27	15096049
Effect of amine ligand bulk on the interaction of methionine with platinum(II) diamine complexes.	2004-02-09	14753844
Evolution of enzymatic activity in the enolase superfamily: functional studies of the promiscuous o-succinylbenzoate synthase from Amycolatopsis.	2004-01-13	14705949
Free radical reactions of methionine in peptides: mechanisms relevant to beta-amyloid oxidation and Alzheimer's disease.	2003-11-12	14599209
Temperature dependence of the kinetics of the acylase hydrolysis reaction by differential stopped flow microcalorimetry.	2003-10-01	12963049
Identification and characterization of a new gene from Variovorax paradoxus Iso1 encoding N-acyl-D-amino acid amidohydrolase responsible for D-amino acid production.	2002-10	12354118
Importance of product inhibition in the kinetics of the acylase hydrolysis reaction by differential stopped flow microcalorimetry.	2002-09-15	12419341
L-methionine inhibits reaction of DNA with anticancer cis-diamminedichloroplatinum(II).	2002-09-10	12206671
Control of cytochrome C redox potential: axial ligation and protein environment effects.	2002-05-15	11996572
Cystathionine pathway-dependent cytotoxicities of diethyl maleate and diamide in rat and human hepatoma-derived cell cultures.	2002-02-06	11827570
Specific enhancement of acylase I and acylpeptide hydrolase activities by the corresponding N-acetylated substrates in primary rat hepatocyte cultures.	2002-02	12000146

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:58:21 GMT 2025` Edited by `admin` on `Mon Mar 31 21:58:21 GMT 2025`
Record UNII	F63297MHIR
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

METHIONINE, N-ACETYL-, SODIUM SALT

Preferred Name

English

ACETYLMETHIONINE SODIUM

Systematic Name

English

L-METHIONINE, N-ACETYL-, MONOSODIUM SALT

Systematic Name

English

Acetylmethionine sodium [WHO-DD]

Common Name

English

SODIUM N-ACETYL-L-METHIONINE

Systematic Name

English

Code System Code Type Description

EVMPD

SUB12724MIG