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Details

Stereochemistry ACHIRAL
Molecular Formula C17H14O4
Molecular Weight 282.2907
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 4',7-DIMETHOXYISOFLAVONE

SMILES

COC1=CC=C(C=C1)C2=COC3=C(C=CC(OC)=C3)C2=O

InChI

InChIKey=LPNBCGIVZXHHHO-UHFFFAOYSA-N
InChI=1S/C17H14O4/c1-19-12-5-3-11(4-6-12)15-10-21-16-9-13(20-2)7-8-14(16)17(15)18/h3-10H,1-2H3

HIDE SMILES / InChI

Molecular Formula C17H14O4
Molecular Weight 282.2907
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

4',7-Dimethoxyisoflavone is an isoflavone related to soybean isoflavone daidzein. Unlike many of its analogs, 4',7-Dimethoxyisoflavone is reported to possess antifungal activity, but unlike structurally related compounds is inactive against H. pylori.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone.
2010-01
Tricarbon-yl(η-4',7-dimethoxy-iso-flavone)chromium(0).
2009-10-10
Conferols A and B, new anti-inflammatory 4-hydroxyisoflavones from Caragana conferta.
2009-04
A new chalcone glycoside from Rhamnus nipalensis.
2008-12
Isoflavones promote mitochondrial biogenesis.
2008-05
Cytotoxic constituents from Butea superba Roxb.
2007-01-19
Biotransformation of isoflavones by the larvae of the common cutworm (Spodoptera litura).
2006-05
Immunoassay for biochanin A.
2004-11
A new coumaronochromone from Sophora japonica.
2002-03
Patents

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
The test fungi were isolated on potato dextrose agar (PDA) medium from their respective hosts. Seven to ten-day-old cultures were used in this experiment. A solution of 4',7-dimethoxyisoflavone was placed on a grease-free glass slide. Fungal spores were mixed in the solution with the help of a sterile inoculation needle. The slides were later placed in the moist chamber made by placing two sterile moist filter papers on the lid and base of Petri plates. Such slides were then incubated at 25±2℃ for 24 h for germination. Alternaria brassicae was the most sensitive as complete inhibition of germination was observed in all the concentrations (100, 200, 250, 500, 750 and 1000 ppm) of the chemical.
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:26:48 GMT 2025
Edited
by admin
on Mon Mar 31 19:26:48 GMT 2025
Record UNII
F5547DW3CO
Record Status Validated (UNII)
Record Version
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Name Type Language
4',7-DIMETHOXYISOFLAVONE
Common Name English
4',7-DIMETHOXYLISOFLAVONE
Preferred Name English
ISOFLAVONE, 4',7-DIMETHOXY-
Common Name English
FORMONONETIN METHYL ETHER
Common Name English
FORMONONETIN 7-O-METHYL ETHER
Common Name English
4H-1-BENZOPYRAN-4-ONE, 7-METHOXY-3-(4-METHOXYPHENYL)-
Systematic Name English
7,4'-DIMETHOXYISOFLAVONE
Common Name English
DI-O-METHYLDAIDZEIN
Common Name English
Code System Code Type Description
CAS
1157-39-7
Created by admin on Mon Mar 31 19:26:48 GMT 2025 , Edited by admin on Mon Mar 31 19:26:48 GMT 2025
PRIMARY
PUBCHEM
136419
Created by admin on Mon Mar 31 19:26:48 GMT 2025 , Edited by admin on Mon Mar 31 19:26:48 GMT 2025
PRIMARY
FDA UNII
F5547DW3CO
Created by admin on Mon Mar 31 19:26:48 GMT 2025 , Edited by admin on Mon Mar 31 19:26:48 GMT 2025
PRIMARY
EPA CompTox
DTXSID90151171
Created by admin on Mon Mar 31 19:26:48 GMT 2025 , Edited by admin on Mon Mar 31 19:26:48 GMT 2025
PRIMARY