Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C7H10N2O4 |
Molecular Weight | 186.1653 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=C(C[C@@H](N)C(O)=O)C(=O)NO1
InChI
InChIKey=UUDAMDVQRQNNHZ-RXMQYKEDSA-N
InChI=1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)/t5-/m1/s1
Molecular Formula | C7H10N2O4 |
Molecular Weight | 186.1653 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/6133955
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6133955
AMPA, D- or R-AMPA is an inactive isomer of (RS)-AMPA.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Effect of glutamate receptor antagonists on suckling-induced prolactin release in rats. | 2003 Jul |
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Pain-related synaptic plasticity in spinal dorsal horn neurons: role of CGRP. | 2006 Sep 26 |
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3D-QSAR studies for the binding affinity toward (R, S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-propionic acid receptor. | 2008 Sep |
|
Facilitation of synaptic transmission and pain responses by CGRP in the amygdala of normal rats. | 2010 Feb 8 |
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6133955
L-AMPA was more effective (IC50 = 0.6 microM) than D-AMPA (IC50 = 4.8 microM) in displacing racemic [3H]AMPA from binding sites on rat brain synaptic membranes in agreement with their relative in vivo excitatory potencies.
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:49:28 GMT 2023
by
admin
on
Sat Dec 16 09:49:28 GMT 2023
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Record UNII |
F45TJ02EL1
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Record Status |
Validated (UNII)
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Record Version |
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-
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F45TJ02EL1
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83654-13-1
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admin on Sat Dec 16 09:49:28 GMT 2023 , Edited by admin on Sat Dec 16 09:49:28 GMT 2023
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