SPHINGOSINE-1-PHOSPHATE LYASE 1

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 23:39:22 GMT 2025` Edited by `admin` on `Tue Apr 01 23:39:22 GMT 2025`
Protein Type	ENZYME
Protein Sub Type	LYASE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	F2W22R3DQE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SPHINGOSINE-1-PHOSPHATE LYASE 1

Common Name

English

HSPL

Preferred Name

English

S1PL

Common Name

English

SPL 1

Common Name

English

S1P LYASE

Common Name

English

SP-LYASE 1

Common Name

English

SPHINGOSINE-1-PHOSPHATE ALDOLASE

Common Name

English

KIAA1252

Common Name

English

Code System Code Type Description

EC (ENZYME CLASS)

EC 4.1.2.27

Created by admin on Tue Apr 01 23:39:22 GMT 2025 , Edited by admin on Tue Apr 01 23:39:22 GMT 2025

PRIMARY

FDA UNII

F2W22R3DQE

Created by admin on Tue Apr 01 23:39:22 GMT 2025 , Edited by admin on Tue Apr 01 23:39:22 GMT 2025

PRIMARY

CAS

625262-65-9

Created by admin on Tue Apr 01 23:39:22 GMT 2025 , Edited by admin on Tue Apr 01 23:39:22 GMT 2025

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UNIPROT

O95470

Created by admin on Tue Apr 01 23:39:22 GMT 2025 , Edited by admin on Tue Apr 01 23:39:22 GMT 2025

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Related Record Type Details


					C5AGI979T7

LX-2931

INHIBITOR -> TARGET

Structural Modifications

Modification Type	Location Site	Location Type	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_564]	SITE_SPECIFIC	DEXFOSFOSERINE	VI4F0K069V
AMINO_ACID_SUBSTITUTION	[1_353]	SITE_SPECIFIC	N6-(PYRIDOXAL PHOSPHATE)LYSINE	QM00M3504A
AMINO ACID SUBSTITUTION	[1_356] [1_366]	SITE_SPECIFIC	3-NITRO-L-TYROSINE	7COY1HA6HK
AMINO_ACID_SUBSTITUTION	[1_353]	SITE_SPECIFIC	N6-(PYRIDOXAL PHOSPHATE)LYSINE	QM00M3504A

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL